George Jr.: Hey, now that you're treating him like an adult, can I have his allowance?
George Sr.: That allowance is for chores, which you already don't do.
George Jr.: Come on. We all know I'm your favorite.
Meemaw: You're not even his third favorite.

Sheldon: Do people know about this?
Meemaw: Sheldon, what's on a person's face is not always what's in their heart.
Sheldon: Well, this changes everything. How do you know who to trust?
Meemaw: You don't. That's what makes life interesting.

George Sr.: You don't always win in life, he needs to learn that.
Mary: I know, but these are big feelings for a little boy.
George Sr.: They're feelings everybody has. It's part of growing up.
Mary: I guess.
Sheldon: Poodle poop!
Meemaw: Okay. Somebody's got to teach this kid to swear, it's embarrassing.

Meemaw: Okay, I'm here. What's up?
George Sr.: Sheldon won't get out of bed, and I'm gonna be late for work. He's gonna be late for school.
Meemaw: So you want me to get him up and drive him?
George Sr.: Yeah.
Meemaw: I like it better when I just come eat your food and leave.

Mary: Mom, can you make the salad?
Meemaw: Sure.
George Sr.: Hey, don't put in any of those little tomatoes.
Meemaw: Hey, I don't tell you how to impersonate a lump of clay. You don't tell me how to make a salad.

Sheldon: Do you think a Spock could become a Kirk?
Meemaw: Well, in my experience, most people stay the miserable bastards they are their whole entire life. But I have seen some folks change.

George Sr.: If we take him to a shrink, it feels like we're admitting something's wrong with him.
Mary: He hasn't had solid food in five weeks.
Meemaw: Well, if there is something wrong with him, it ain't constipation.

Meemaw: I'm Sheldon Cooper's grandmother and, uh, I need to take him out of school today.
Diane: Sure. What's the reason?
Meemaw: His Aunt Emelda's not doing well, and has asked to see him 'fore she goes.
Diane: Oh, I am so sorry. Does she want to see his older brother also?
Meemaw: Nah. She doesn't like him as much.

Meemaw: Okay, here you go. I got you a shovel and a bucket and some gloves.
Sheldon: Did you check the gloves for spiders?
Meemaw: Is this my first day as Meemaw?

Mary: It's not funny.
Meemaw: Oh, come on, now. Sheldon in detention? That's funny.

Meemaw: Mind if I take a crack at catching the Road Runner?
Mary: What are you gonna do that I couldn't do?
Meemaw: Oh, a little trick I learned trying to get prairie dogs out of the hole. Of course we'd whack off their heads with a golf club. I'm not gonna do that to Sheldon.

Meemaw: I could buy it for him, and then y'all could pay me back when you can.
George Sr.: Okay, Connie, now you're just insulting me.
Meemaw: Well, that was not my intention, but I'm glad to hear it.

George Sr.: The little Sparks girl?
Mary: You're kidding. She seems so sweet.
George Jr.: He says she slaps him around, takes his lunch money. She even put a tadpole down his shirt.
Meemaw: Poor kid. He tucks in those shirts.

Meemaw: Look, you haven't even gotten to the worst part of it yet. They're gonna leave home. They're gonna move to another city.
Mary: Oh, Lord.
Meemaw: They're gonna tell you their loser boyfriend has knocked them up. Just to be clear, that would be you.
Mary: Sorry.
Meemaw: Turned my hair gray overnight.
Mary: I said sorry. Clearly, you're not in the mood to help.
Meemaw: Listen, it's hard being a parent, but if you do it right, they don't need you anymore.
Mary: Well, I don't like that. I get it, but I just don't like it.
Meemaw: Well, I'd point out, you'll always have your husband, but you want me to be "helpful".

Meemaw: So I saw a lawyer today.
Mary: Why?
Meemaw: I'm putting together my last will and testament.
George Sr.: We're gonna miss ya.
Mary: George.
Meemaw: Don't worry. I ain't leaving him squat.

Mary: I don't want my little boy in some car with a teenager behind the wheel.
George Sr.: All high school kids drive.
Mary: Yeah? Well, I don't like it. Would you let me get in a car with a stranger when I was young?
Meemaw: Well, nobody ever asked you out, so it didn't really matter.

Meemaw: What kind of Texan drinks pink wine?

Sheldon: Okay, here's the plan. End your relationship with Coach Ballard, date Dr. Sturgis again, get him to love you more than ever, then when he least expects it, break his heart and say, "That's for Sheldon."
Meemaw: Great plan.
Sheldon: You think so?
Meemaw: For the sake of this car ride, sure.

Sheldon: I've been corresponding with Dr. John Sturgis at East Texas Tech. He said I could audit his course.
Meemaw: You're pen pals with a stranger? Is this okay?
Sheldon: He's not a stranger. He's a famous scientist. He carbon-dated the oldest human feces.
Meemaw: That ain't strange.

Brenda Sparks: Well, I'm sorry, but you shouldn't be inferring there's something wrong with my Billy.
Meemaw: Darlin', there's no inferring. I've seen the boy sitting in the dirt eating his own belly button lint.