Sheldon: Hello, Sam, Keith, big bag of dirty underpants.

Sheldon: Now my mom wants them to get married, but it doesn't sound like the girl's willing.
Dr. Linkletter: Why are you still talking to me?
Sheldon: You and I just click.

Missy: What else you bringing her?
Sheldon: Toothbrush, toothpaste, pajamas, and these feminine napkins. Is one box enough?
Missy: Should be plenty.
Sheldon: I hope so. She's been awfully moody.
Missy: Maybe you aren't the best person to be handling this.
Sheldon: Agreed, but I'm all she's got.
Missy: I feel like you should tell Mom.
Sheldon: I promised I wouldn't.
Missy: I know, but this sounds serious.
Sheldon: I got her a toothbrush and lady pads, what more can I do?

Paige: So, did you guys get, like, assigned to look after Sheldon or something?
Darren: No, he ended up in the room next door.
Oscar: So we took him in, like a dog.
Paige: Him being so young isn't, like, weird?
Sheldon: I'm basically 50.
Darren: And we're basically 12, so it all works out.

Sheldon: Are there any discounts available?
Fran: Are you a member of any frequent-flier programs?
Sheldon: No, I've never flown before.
Fran: Well, ways to keep the cost down are: flying on weekdays, multiple layovers... Or, this probably doesn't apply, but airlines offer special fares if there's been a death in the family.
Sheldon: Interesting. May I use your phone?
[elsewhere:]
Meemaw: [answering phone] Hello?
[back:]
Sheldon: What else you got?

Pastor Jeff: Actually, Mary, can I speak to you for a sec?
Mary: Sure. Um, I'll be right there.
Meemaw: Yeah, make it quick. I don't want to miss kickoff.
Sheldon: [groans] Church and football? At least 60 Minutes is on tonight.

Adult Sheldon: My sister had taken a different path with her money.
Sheldon: What is that?
Missy: It's a cotton candy machine.
Sheldon: Why?
Missy: It's a machine that makes free cotton candy.
Sheldon: It's not free, you paid for it.
Missy: Meemaw paid for it. And it's still better than lame stocks.
Sheldon: You're going to end up with a stomachache while I get to be part of America's favorite electronics retailer.

Sheldon: How do you recommend I "suck it up"?
Missy: I don't know, when you don't get your way, shut up and move on.
Sheldon: Is that what you do?
Missy: Yeah.
Sheldon: And that's why you don't have a computer.

Captain: [v.o.] Ladies and gentlemen, this is your captain speaking. We're expecting a smooth flight to Los Angeles. Before we take off, please direct your attention to the flight attendants as they review some important safety procedures.
Sheldon: "Safety procedures"? Oh, baby.

Sheldon: I think we've been lied to about California. No one on this campus is tan at all.
George Sr.: No, they are not.

Jana: I think I'm gonna go.
George Jr.: Okay.
Sheldon: Hola, senorita. She's in my Spanish class.
Jana: I'll call you later.
Sheldon: Te veo manana en la clase de espanol.
Jana: What?
Sheldon: That means, "See you tomorrow in Spanish class." I was going to ask how you thought you did on Friday's quiz, but I'm guessing the answer is no bueno. Adios.

Adult Sheldon: I never understood why kids didn't like being sent to the principal's office. I thought it was great.
Principal Petersen: Sheldon, you are a remarkable young man.
Sheldon: Thanks, and you're a remarkable old man.
Mary: Sheldon.
George Sr.: So you sure he's got all the credits he needs?
Principal Petersen: Yeah, between his coursework and his AP tests, he's met all of his academic requirements. He even managed to get a good grade in P.E.
Sheldon: I earned extra credit snitching on kids who were smoking behind the equipment shed.
Principal Petersen: I don't have to buy cigarettes for a year.

Sheldon: Imagine all the stimulating conversations that must go on at these tables.
George Sr.: I bet.
Sheldon: I can see myself going here one day.
George Sr.: I think you'd fit right in.

Sheldon: I guess I need to call and let him know what a bonehead mistake he made.
George Sr.: There's probably a nicer way to say it.
Sheldon: Did you hear how massive his neutrinos were? We're well into bonehead territory.
George Sr.: Sheldon, you don't need to be rude to him.
Sheldon: When am I rude?
[flashback to Sheldon watching a Missy combs the hair of her Cabbage Patch Doll:]
Sheldon: Stay a child as long as you can. Adulthood will not be kind to you.
[flashback to Sheldon looking at Meemaw's leg:]
Sheldon: Neat. The veins on your calf look like a road map of Texas.
[flashback to Sheldon at dinner time:]
Sheldon: Did you make this taste bad so Dad would lose weight?
[present:]
Sheldon: Fine. I'll be polite. But I still think we could go to San Antonio using Meemaw's leg.

Meemaw: What's going on here?
Sheldon: Wesley Crusher was just accepted into Starfleet Academy, and for his final mission, he's accompanying Picard on a shuttle mission to Pentarus Five.
Meemaw: No. I mean who's your friend?
Sheldon: Oh, he's not a friend. He's a stranger. I met him on a Star Trek bulletin board. He had a copy of the episode Georgie taped over and brought it here.

George Sr.: This is the moment we lost that game. But one bad play doesn't mean you give up. We had plenty of time to turn it around, but y'all decided it was over. I don't want to ever see that happen again. Next time something seems out of your reach, you do not quit. You just dig deeper.
Sheldon: [appears out of nowhere] Does that mean if I find an affordable flight to California, we can go?

Paige: You got a roommate?
Sheldon: No, it's a single.
Paige: I have a chaperone. Mona. She's, like, 30. It's the worst.
Sheldon: Why do you need a chaperone?
Paige: Maybe they think I'm, like, some kind of troublemaker.
Sheldon: As the owner of the face you punched, they're right.

Fran: Hi. Can I help you?
Sheldon: I'm trying to find the cheapest flight to California for me and my father.
Fran: Okay. Well, have a seat. You lookin' to go to Disneyland?
Sheldon: The only ride I'm interested in is the intellectual roller coaster of Stephen Hawking's mind.
Fran: And where is that located?
Sheldon: Well... Stephen Hawking's head. But that will be at Caltech in Pasadena.

Paige: You didn't stay for the Q and A.
Sheldon: I had no Q's, and therefore, needed no A's.

Adult Sheldon: While my sister was starting her business, I was trying to save mine.
Sheldon: [on the phone] Hello, this is Sheldon Cooper. May I speak to CEO John Roach, please? It's regarding our stock taking a small dip, and I'd like to hear his game plan. Well, I'm busy, too, but I made the time to call. Fine, may I please speak to your COO? CFO? CTO? Hello?