Adult Sheldon: My sister encouraged me to embrace adolescence as a journey of scientific discovery. I stood before a whole new teenage world of music, slang words and even clothing styles. [Sheldon removes a red Flash t-shirt] Pretty groovy, huh?
[Sheldon stands in front of his bedroom mirror wearing the red Flash t-shirt over a blue undershirt]
Sheldon: Wow, I might look too cool.

Missy: Sheldon, there has to be stuff you're excited to do.
Sheldon: Of course. Getting my PhD, winning the Nobel Prize, getting to meet Professor Proton, working with Stephen Hawking.
Missy: Okay, so, when you start to get upset, focus on that stuff.
Sheldon: But... what if I grow up and none of those things ever happen?
Missy: All you can do is try and find out.
Sheldon: Those are the fundamentals of the scientific method.
Missy: No doy.

Sheldon: Maybe we should go to the emergency room.
Missy: It's just a pimple. Pop it.
Sheldon: No.
Missy: I'll do it. I like when it hits the mirror. Now hold still.
[fantasy: A.V. and Pus are now standing, with no chair or stool in sight:]
A.V.: It seems we've reached the end of our time with Sheldon. [Pus is holding two suitcases] But it's never truly goodbye. We'll be back in moments of stress. Like a big test. Or my personal favorite, school picture day... [they disappear in an explosion of yellow pus, leaving the two suitcases]

Missy: What's the problem?
Sheldon: My childhood is ending.
Missy: So?
Sheldon: Look at everyone around us... they're all miserable. Mom and Dad are unemployed. They're constantly fighting. Georgie's having a child.
Missy: First of all, no one's having a kid with you, ever.
Sheldon: Don't be so sure. With this intellect, my genetic material will be a hot commodity. [Missy groans] That's how I feel.

[After Sheldon wakes up from his dream, he sits up in bed and uses his rope/pulley system to knock on Missy's bedroom wall.]
Missy: [over walkie-talkie] I hate you. This better be an emergency.
Sheldon: My pimple has me concerned about the future.
Missy: Not an emergency. Good night.
Sheldon: But we're twins and we have a special bond, so you can't ignore me in my time of need.
Missy: Watch me.
Sheldon: And I'm scared.
Missy: Damn it.

[dream sequence:]
Sheldon as George: Something weird's going on.
Sheldon as Mary: Not now, George. I have to finish making the kids' lunches, get them to school, and then go looking for a new job.
Sheldon as George: But I'm turning into my father.
Sheldon as Mary: I don't have time for whatever crisis you're going through. And why are you still wearing that uniform? You don't even work there anymore.
Sheldon as George: Well, maybe nothing else was clean.
Sheldon as Mary: You're a grown man... you can wash your own clothes.
Sheldon as Meemaw: Would you two quit fighting? You ain't the only one with problems.
Sheldon as George: For God's sakes, why are you always here?
Sheldon as Mary: Don't be mean to her.
Sheldon as George: You're mean to me.
Sheldon as Meemaw: I'm just dropping off your mail, fatass. And it's nothing but bills.
Sheldon as Georgie: Just got back from the baby doctor. Mandy's having triplets. Dang it.
Sheldon as George: How we gonna handle all this?
Sheldon as Mary: I guess Sheldon's gonna have to drop out of school and get a job.
Sheldon as Meemaw: I hear the coal mine's hiring.
Sheldon as Georgie: Ain't that too messy for him?
Sheldon as Meemaw: The boy's got to grow up sometime.
Sheldon as George: Ain't that the truth.
Sheldon as Mary: He's got that nasty pimple, so he's well on his way.
[fantasy:]
A.V.: Whoa. Heavy stuff. But like a... caterpillar transforming into a butterfly, things need to get a little weird along the way. [Pus puts the blue caterpillar figure he was holding under a napkin and pulls out a blue butterfly figure] [laughs] How can people not like us? That was awesome. And Pus is available for children's parties. [Pus rubs his fingers together to signal cash]

Sheldon: But what if it's scratchy and it's all I can think about?
Dr. Linkletter: It's just armpit hair.
Sheldon: Well, I don't even have it yet and it's already consuming my thoughts.
President Hagemeyer: All right, Sheldon, you are a smart kid. Now, you had to know that this was gonna happen eventually.
Sheldon: I'm a smart kid now, but what will I be in a year?
President Hagemeyer: A smart young man.
Sheldon: And then a smart adult. With money problems and marital strife and every other problem you can think of. I'll probably have a beer belly. Or root beer belly.

Wendy: This is... just a pimple.
Sheldon: Well, how can you be sure it isn't chickenpox? Or smallpox? Or monkeypox, which I know sounds made-up, but is very real.
Wendy: Have you been near any monkeys?
Sheldon: No.
Wendy: Try benzoyl peroxide. It's over the counter.
[fantasy: A.V. and Pus:]
A.V.: Oh, no, not... benzoyl peroxide. [high-pitched] I'm melting! I'm melting! [normal voice] Give me a break.
[reality:]
Sheldon: But a pimple is a sign of puberty, and I'm showing no other indicators. No armpit or chest hair, and I have so little interest in the opposite sex, I barely noticed you're a woman.
Wendy: Thank you.

Sheldon: What is that? A bug bite?
[fantasy: a man (Penn Gillette) addresses the camera from a large chair:]
A.V.: Hello, allow me to introduce myself. I am Acne Vulgarus. More commonly known as the pimple. Frankly, neither name paints a very pretty picture, but such is the life of a pustule. [a smaller man (Teller) is seated on a stool] And this is my longtime colleague, Pus. Now, we're usually associated with, uh, ugliness and discomfort, but I would argue we're actually a symbol of growth. In this case, Sheldon Cooper's ascent... or descent... into adulthood. Kind of a signpost that says, "You are now entering puberty." [Pus holds up a sign reading exactly that] Yeah, like that.

Sheldon: Dr. Linkletter, may I speak with you?
Dr. Linkletter: If I say no, will you leave?
Sheldon: No.
Dr. Linkletter: Then why even ask?
Sheldon: It's called manners.

Mary: Doesn't look like a bug bite.
Missy: It's probably a pimple.
Sheldon: It's not, I don't get those.
[fantasy: A.V. continues to address the camera from his chair, while Pus is blowing up a balloon while seated on a stool:]
A.V.: As you might expect, we pimples are not very fond of popping things, but I was about to burst this young man's bubble. [Pus pops the balloon]
[reality:]
Missy: Oh, yeah, that's a zit.
Sheldon: No, it's not. My hygiene is impeccable.
Missy: Zit.
Mary: Everybody gets 'em sooner or later, baby.
Sheldon: I'm not everybody.
[fantasy:]
A.V.: No one is ever happy to see me. My therapist says that's their problem, not mine. [Pus rolls his eyes] But, honestly, it hurts. [Pus makes a mocking gesture] Pus? This is supposed to be a safe space. [Pus continues mocking A.V.]

Mary: Let's say grace.
Sheldon: Hang on, safety first. [puts mittens on]
George Jr.: When are you gonna get over that?
Sheldon: I would think recent events would make you value protection.
Mary: Enough.

Adult Sheldon: I was struggling to focus and needed help. Luckily, there was someone on campus I could always count on to lend a friendly ear. A second mom, if you will.
President Hagemeyer: What now?
Sheldon: You said if I ever had a problem, I could come to you and you'd fix it.
President Hagemeyer: When did I say that?
Sheldon: September 13th, 1991. You had just eaten a poppyseed bagel and had one stuck in your teeth.
President Hagemeyer: I'll take your word for it.
Sheldon: It was right here. How did it not make you crazy? It made me crazy.
President Hagemeyer: What do you want?
Sheldon: My family's falling apart.
President Hagemeyer: Oh, I'm sorry to hear that. Uh... what do you want me to do?
Sheldon: Fix it.

Mary: Should you really be reading in the car, baby?
Sheldon: I'll be fine.
Mary: You sure? You're not the one who'll have to clean up the oatmeal back there.
Sheldon: I said I'll be fine. And it's the blueberries you should be worried about.
Mary: Well, you're in a mood.
Sheldon: Maybe because there was so much bickering going on at home that I couldn't study.
Mary: Oh, I'm sorry if our family problems are getting in the way of your schoolwork.
Sheldon: I accept your apology. [vomits]
Mary: Oh...
Sheldon: Yep, blueberries.

George Jr.: You can't go around hitting people.
Missy: I had to do something.
Sheldon: Me too.
Missy: What did you do?
Sheldon: I ran and told the nearest adult.
George Jr.: I don't want you getting in trouble for me.
Missy: But Danny says you're going to hell.
George Jr.: I'm there now. Promise me.
Missy: Fine.
George Jr.: And I know you ain't hitting nobody.
Sheldon: You are correct, sir.

Sheldon: If we're switching religions, may I recommend Judaism.
Mary: Why?
Sheldon: Both William Shatner and Leonard Nimoy are Jewish.
George Sr.: So?
Sheldon: Isn't that enough?

Billy Sparks: What's going on?
Missy: What's going on is people are talking about my brother behind my back instead of saying it to my face.
Sheldon: She's talking about Georgie, not me. People talk about me behind my back, but it's about how smart I am.

Mary: Let's say grace. Bless us, Lord, for the food we are about to receive, and bless the hands that prepared it. Amen.
All: Amen.
Sheldon: I told Dr. Linkletter about Georgie.
George Jr.: Why'd y'all tell Sheldon?
Missy: They didn't. I figured it out.
George Jr.: Great. Now everyone knows.
Mary: Not everyone.
Sheldon: Just us and Dr. Linkletter.

Sheldon: Now my mom wants them to get married, but it doesn't sound like the girl's willing.
Dr. Linkletter: Why are you still talking to me?
Sheldon: You and I just click.

Sheldon: Sorry again for being distracted earlier.
Dr. Linkletter: And I'm so sorry you got locked out. I don't know how that happened.
Sheldon: My brother got a girl pregnant. My mom wanted me to promise I wouldn't tell, but I never did, so technically, I'm not breaking my word.
Dr. Linkletter: I don't care.
Sheldon: Thank you. But it's a secret, so please don't tell anyone.
Dr. Linkletter: Don't you have somewhere to go?
Sheldon: No.