Georgie: A bill? Really?
George: Room and board, buddy.
Georgie: $50 a month for food?
George: The way you eat, I should've gone $50 a week.
Georgie: Laundry services?
George: Your poor mother has to touch your underwear.
Georgie: What's the $10 a month "peema" charge?
George: Oh, P-I-M-A, that's a "Pain in My Ass" tax. My way of getting compensated for you taking years off my life.

Adult Sheldon: That was the first time I held my father's hand. I wouldn't touch my brother's hand until seventeen years later, thanks to the invention of Purell.

Mary: You smoke marijuana?
Sheldon: Mom!
Libby: No, ma'am.
Tam: Just say no. [Mary shoots him an unimpressed look]

Tam: You see a large red button. What do you do?
Billy Sparks: I press it.
Tam: The floor opens up and you plunge into a 60-foot pit.
Billy Sparks: I fly out. Up, up, and away!
Sheldon: Again, you're not Superman in this game; you're Superman for Halloween.
Tam: Which isn't till next week.
Billy Sparks: So I'm in a pit.
Tam: You're in a pit.
Billy Sparks: Then I blast my way out with my super breath! [BLOWING]
Sheldon: Just let him do it.

Adult Sheldon: I've fought many digital battles in my life, but none are as memorable as this first one with my Meemaw. By handing me the controller, she was telling me she believed in me. That inside my small, fragile frame beat the heart of a hero.

Georgie: How come when I'm sick it's no big deal, but when Sheldon gets sick you act like it's the end of the world?
Mary: Because he's a fragile little boy and you're gettin' to be a big, strong man.
Georgie: That's true. Puberty has done right by me.

Missy: Do you believe in God?
Georgie: Yeah.
Missy: But in the Bible, he does all kinds of mean stuff. If he's good, why would he do that?
Georgie: Maybe he just wants to show he's in charge. Hulk Hogan's nice, but in the ring, he will mess you up.
Missy: That's either really smart or really stupid.
Georgie: That's what I do.
Missy: Do you ever wonder if it's all made-up?
Georgie: Look, this is Texas. We like football. We like God. And beef. Beef's up there, too.
Missy: But how do you know there's a God?
Georgie: See that girl dancing in them shorts? There's a God.

Mary: Too bad. We are going.
Sheldon: Class is starting tomorrow. I'm not going anywhere.
Mary: Sheldon, do not argue with me. You are going home.
Sheldon: Mom, the people of Germany are obsessed with rules and devoid of humor. I am home.

George: If we take him to a shrink, it feels like we're admitting something's wrong with him.
Mary: He hasn't had solid food in five weeks.
Meemaw: Well, if there is something wrong with him, it ain't constipation.

Adult Sheldon: I never did get to see a launch in person, but that was the best trip I ever had. I wish I had told my father while he was alive.

Adult Sheldon: A primary feature of quarks is that they're always bonded together, but in that moment, I felt like a neutrino, destined to be alone forever.
[Montage of young Leonard, Penny, Raj, Howard, Bernadette and Amy at that moment]
Adult Sheldon: Thankfully, I was wrong.

Mary: You understand that some people are going to be intimidated by you, because of how smart you are?
Sheldon: Or maybe they'll recognize my intellect and make me their leader.

Adult Sheldon: I would go on to draw up such contracts throughout my life. With roommates. With my wife. Even with my own children.

Tam: Spending the Thanksgiving weekend working in my family's convenience store, I observed my father and mother working from 6:00 in the morning till 10:00 at night. My hypothesis was that economic advancement for immigrant families is more important than celebrating a holiday where people eat until they pass out in front of the TV.
Mr. Givens: All right, Tam. Well, based on your observations and hypothesis, were you able to make a prediction?
Tam: Yes. At some point, my father would die prematurely from stress. And my mother will come live with me, where she will constantly disapprove of my hot, blonde, American wife.
Mr. Givens: Okay. Uh, I think we all learned something there. Uh, thank you, Tam.

Mary: Remember, it's a school night, so his bedtime is 7:30.
Dr. John Sturgis: Mine, too!