Adult Sheldon: A primary feature of quarks is that they're always bonded together, but in that moment, I felt like a neutrino, destined to be alone forever.
[Montage of young Leonard, Penny, Raj, Howard, Bernadette and Amy at that moment]
Adult Sheldon: Thankfully, I was wrong.

Adult Sheldon: I didn't realize until years later that my father was only asking questions about lightning and thunder to cheer me up. In fact, he would often pretend to be dumb just to make me feel better.

Adult Sheldon: Visiting Tam's house for the first time was an emotional roller coaster.
For example, it's traditional in Vietnamese homes to have gruesome religious iconography near the entrance. I did not like that.
However, it's also customary to not wear shoes around the house for sanitary reasons. I did like that.
Interestingly, one of the main ingredients in Vietnamese cooking is an extremely pungent condiment known as fish sauce. I did not like that.
But before every meal, it's common for everyone to wash their hands and face. I did like that.
Forks are not customary in a Vietnamese household. I did not like that.
And instead of napkins, there was one towel for everyone to share at the table. Seriously, what are they thinking?

Adult Sheldon: I've fought many digital battles in my life, but none are as memorable as this first one with my Meemaw. By handing me the controller, she was telling me she believed in me. That inside my small, fragile frame beat the heart of a hero.

Meemaw: John?
Dr. John Sturgis: Hello.
Meemaw: What- What're you doing?
Dr. John Sturgis: I was doing tai chi and then I realized that I was continually being bombarded by subatomic particles and it behooves me, perhaps, to pay slightly closer attention to them. Maybe "chi" is the ancient Chinese word for the subatomic universe.
Meemaw: You're scaring me, John.
Dr. John Sturgis: Well, there's nothing to be scared of. Tomorrow, somebody will win the Nobel Prize about these particles not me. But I'm experiencing them firsthand [LAUGHS] which could be better.
Meemaw: Why don't you come down and experience them on the floor?
Dr. John Sturgis: I think I just felt a neutrino. [LAUGHING] You know, neutrinos are interesting. They never bond with anything, they're always alone. I think that one went right through my pants.
Meemaw: All right, why don't we go downstairs, and I'll fix us both a nice cup of hot tea and you can tell me all about it. Please?
Dr. John Sturgis: Okay. It was my dream to win the Nobel, and I'm not going to. I bet Sheldon will.
Meemaw: That'll be something.
Dr. John Sturgis: Yeah.

Georgie: A bill? Really?
George: Room and board, buddy.
Georgie: $50 a month for food?
George: The way you eat, I should've gone $50 a week.
Georgie: Laundry services?
George: Your poor mother has to touch your underwear.
Georgie: What's the $10 a month "peema" charge?
George: Oh, P-I-M-A, that's a "Pain in My Ass" tax. My way of getting compensated for you taking years off my life.

Sheldon: Which scientists are you rooting for?
Dr. John Sturgis: Oh, I don't have a favorite. There's so much good work being done.
Sheldon: I think it's time Frederick Reines finally gets his due for the neutrino.
Dr. John Sturgis: I suppose he has a shot.
Sheldon: I should think so, he confirmed the neutrino's existence 35 years ago. What the heck are they waiting for?
Dr. John Sturgis: Lots of talented people don't get recognized.