Adult Sheldon: It's called perfect cleavage when gypsum separates this cleanly. I was so proud of Tam for not making an immature cleavage joke.
Tam: Look at me, I'm touching cleavage.
Adult Sheldon: Until he made one.

Adult Sheldon: Whoever said the quickest way to a man's heart is through his stomach did not consider his tiny bladder.

Adult Sheldon: My new adult responsibilities began that night. Luckily, a cookbook is nothing more than a set of instructions. And if there's one thing I shine at, it's following instructions.

Sheldon: Why are you eating cereal for dinner?
Billy Sparks: I was hungry, and my parents are in their bedroom kissing.

Sheldon: Which scientists are you rooting for?
Dr. John Sturgis: Oh, I don't have a favorite. There's so much good work being done.
Sheldon: I think it's time Frederick Reines finally gets his due for the neutrino.
Dr. John Sturgis: I suppose he has a shot.
Sheldon: I should think so, he confirmed the neutrino's existence 35 years ago. What the heck are they waiting for?
Dr. John Sturgis: Lots of talented people don't get recognized.

Dr. John Sturgis: I'm glad she's doing well. Tell her I say hi.
Mary: I will do that.
Dr. John Sturgis: Actually, no. Uh, tell her I said hello. "Hi" is a bit, uh, casual. Or wait. Greetings. Just say, uh, "Greetings from John."
Mary: You don't sound sure about that.
Dr. John Sturgis: No, I don't.

Ms. MacElroy: That's sweet of you for asking, but I'd rather stick my finger in a pencil sharpener and crank away.

Missy: What's it like to not believe in God?
Sheldon: It's great. Big fan.
Missy: Are you ever afraid you're wrong?
Sheldon: About religion? Never. About other things? Also never.

Meemaw: You looking for a new church?
Mary: Not yet.
Meemaw: 'Cause I can see you going Catholic. You got a "get thee to a nunnery" vibe.

Meemaw: I got to go open up the gambling room. Can you watch her for about an hour?
Dale: I just had coffee and a bowl of Raisin Bran. Next hour is spoken for.
Meemaw: You could've just said no.
Dale: I'm trying to keep the romance alive.

Mr. Givens: Caltech? Fantastic.
Sheldon: For Caltech? I know.
Mr. Givens: Mm. Well, I'm sure you're gonna do great things.
Sheldon: I hope so. I intend to. I'm being modest. I will.
Mr. Givens: You're taller, but you're still the same.
Sheldon: It's fun, isn't it?
Mr. Givens: Okay. Good luck at Caltech, Sheldon.
Sheldon: I don't believe in luck.
Mr. Givens: Well, here's hoping that a random universe works out in your favor.
Sheldon: Thank you. Bye.
Mr. Givens: Hmm. [to his class] That young man might change the world someday. Or blow it up. Who's to say?

Mary: I don't want my little boy in some car with a teenager behind the wheel.
George: All high school kids drive.
Mary: Yeah? Well, I don't like it. Would you let me get in a car with a stranger when I was young?
Meemaw: Well, nobody ever asked you out, so it didn't really matter.

Meemaw: [singing] Oh, say, does that star-spangled banner, Yet wave-

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

George: You're not gonna make it in this school if you keep ratting people out.
Sheldon: But they were breaking the grooming codes and the dress codes. I saw one boy with a t-shirt that said... [leans in and whispers] "Bite me".
George: Yeah, that's terrible. [Sheldon nods]