Mary: Did you have a tough time when your kids started being independent?
Meemaw: I'll let you know.
Mary: What does that mean?
Meemaw: Means one of 'em is still sitting in my kitchen whining about something.
Mary: Could you be supportive for once?
Meemaw: Yes, watching your kids grow up is hard.
Mary: So how do you handle it?
Meemaw: I find a little bourbon in my coffee does the trick.

Adult Sheldon: My meemaw wrote...
Meemaw: "To my brave Moon Pie. You handled this like a true Texan".
Adult Sheldon: My mom wrote...
Mary: [v.o.] "Shelly, you'll always be my baby, but I'm so proud of the young man you've become. Love, Mom".
Adult Sheldon: And Billy wrote...
Billy Sparks: "Billy".

Mandy: So, you really think my folks'll come around?
Meemaw: I don't know 'em, but babies have a magical power over people, especially grandparents.
Mandy: Is that how you felt when Georgie was born?
Meemaw: Oh, it was love at first sight.
Mandy: And then 17 years later he got me pregnant.
Meemaw: You're not gonna let that go, are you?
Mandy: Nope.
Meemaw: Hmm.

Sheldon: And who says you have to be mature to go to college? I've seen Animal House.
Meemaw: You have?
Sheldon: Well, I've seen the poster. Those people are not college material.

Dr. Linkletter: [answers phone] Grant Linkletter.
Sheldon: Dr. Linkletter, Sheldon Cooper. I need your help reporting an academic crime.
Dr. Linkletter: Sounds serious.
Sheldon: It is. That's why I'm using my serious voice.
Dr. Linkletter: Then I'll use mine as well. [deeper] What's going on?

George Sr.: What do you mean you quit?
Sheldon: It was beneath me.
George Sr.: You need to learn there's nothing wrong with a little hard work.
Sheldon: Hard work is calculating neutrino properties to one percent accuracy. Anyone can wash bolts.
George Sr.: You begged him for that job.
Sheldon: I assumed he'd realize the value of my intellect and put it to good use.
George Sr.: Hang on. You made a commitment. When you say you're gonna do something, you do it.
Sheldon: Well, he could find someone else.
George Sr.: Doesn't matter. This is about you being a man of your word.
Adult Sheldon: I wanted to point out that I couldn't be a man of my word, since I hadn't hit puberty, but he seemed pretty grouchy.

[fantasy:]
Meemaw: John, I'm sorry, I don't mean to push, but I just, I worry about you.
Dr. John Sturgis: You do?
Meemaw: Of course. You know I care about you.
Dr. John Sturgis: That means a lot. The truth is, if I could live in an alternate universe, I'd live in one where we never broke up. I hope it's okay to say that.
Meemaw: It is. Because I wish it, too.
Dr. John Sturgis: Oh, Connie.
Meemaw: Oh, John.
[reality:]
Meemaw: John? John?
Dr. John Sturgis: Huh?
Meemaw: If you could live in an alternate universe, what would it be?
Dr. John Sturgis: Oh, I haven't really given it any thought.

Sheldon: I did it. Missy, I did it!
Missy: [groans] What?
Sheldon: I slept through the night.
Missy: What time is it?
Sheldon: 6:14.
Missy: This is why people hate you.
Adult Sheldon: My sister's crankiness did not dampen my enthusiasm. A chicken may have fractured my arm, but nothing could break my can-do spirit.

Meemaw: Thank you so much, Ira. I really needed this.
Ira Rosenbloom: You're welcome.
Meemaw: We should do it again. What's your Friday night look like?
Ira Rosenbloom: Oh, no, Friday's no good 'cause we're doing inventory at the store.
Meemaw: Oh, okay. Well, how about the weekend?
Ira Rosenbloom: No, no, no, that's not good for me, either.
Meemaw: Are you blowing me off?
Ira Rosenbloom: Is it that obvious?
Meemaw: Well, I don't understand why. I mean, I-I thought we had a nice time.
Ira Rosenbloom: Oh, we did. But you're still hung up on John, and I don't want to have my heart broken again, so I'm gonna respectfully pass.
Meemaw: Unbelievable.
Ira Rosenbloom: I know. It turns out I do have a shred of dignity. [chuckles] I'm as surprised as you are.
Meemaw: [chuckles] I'm not having a good week.

Dr. John Sturgis: This is wonderful. Did you know the term "dive bar" originated because many establishments were below street level, and patrons had to essentially dive down to enter them.
George Sr.: Didn't know that.
Dr. John Sturgis: Well, now you do.

Dr. Linkletter: Thank you for understanding.
President Hagemeyer: And between us, I am counting on you being in charge.
Dr. Linkletter: Excellent.
[cut to:]
President Hagemeyer: You're the alpha dog on this project.
Dr. John Sturgis: Very good. But shouldn't we tell everyone?
President Hagemeyer: Oh, no, no, no, no. I can't be seen as playing favorites. But what's important is that I know and you know.
Dr. John Sturgis: Smart.
President Hagemeyer: But not as smart as you.
Dr. John Sturgis: Oh. [laughs]

George Jr.: See, number one is also pretty funny, 'cause it means taking a leak. [Mary sighs]

Mary: Thank you, Lord, for this little boy.
Sheldon: I knew I could fix it.
Mary: [LAUGHS] Maybe it was you and the Lord.
Adult Sheldon: I don't like sharing credit, but I knew in that moment it wasn't the appropriate time to say it.

Pastor Jeff:And Jacob said: "For I have seen God face to face, and my life is preserved."
Sheldon: Is this an appropriate time to mention that John 1:18 says, "No man hath seen God at any time." Who's right? Jacob or John?
Mary: Let's talk about it in the car.
[Meemaw raises her hand]
Pastor Jeff: Yes, Connie?
Meemaw: My grandson has a question. Let 'er rip, kid.

Sheldon: "If you were not covered by a retirement plan, but your spouse was, see the worksheet on page 14." Try and stop me.

Mary: I've been buying groceries for the church food drive. I think that's it.
Sheldon: Ooh, I bet I could write that off, including the gas it took to drive to the grocery store and then to the church.
George Sr.: With all that driving, maybe she can count her car as a home office.
Sheldon: Sounds aggressive, but I like how you're thinking.

Sheldon: I balanced the rest of the account, and it appears to be a check for $300.
George Sr.: All right, well, let's just put it down for $300 for miscellaneous.
Sheldon: I've never labeled anything miscellaneous in my life.

George Sr.: What do you say we keep this quiet?
Sheldon: You mean like a secret?
George Sr.: No, no, just, you know, something between you and me.
Sheldon: What about Mom?
George Sr.: Mom is on a need-to-know basis.
Sheldon: What if Mom needs to know?
George Sr.: Okay, it's a secret. Just trust me. It is better for everyone if she doesn't know about this.
Sheldon: But I'm not good at keeping secrets.
George Sr.: It's not hard. Just keep your mouth shut.
Sheldon: But I'm not good at keeping my mouth shut.

Adult Sheldon: There was only so much food I could eat, so I started avoiding my mother whenever possible.
George Sr.: [OPENING A CUPBOARD AND FINDING SHELDON] What are you doing in there?
Sheldon: [WHISPERING] Keeping your secret.
George Sr.: You got to pull it together.
Sheldon: This is me pulling it together.
George Sr.: Pull harder.

Adult Sheldon: Avoiding my mother in our own house was proving to be difficult, so it was time to get creative.
Sheldon: Hello. I'd like to book a room in your hotel. I'd be arriving tonight. No, it's just me. Ooh, a queen bed, that sounds fancy. And how much would this room cost? Wow. Is that per month? Per day? By any chance, do you have a children's rate?