Sheldon: The show not only takes place but is also filmed in Los Angeles, California. That's obviously where she's heading. [phone rings]
Meemaw: [answers phone] Cooper residence.
Sheldon: Now, given the amount of time since she's left...
Meemaw: They're okay! [Mary sighs] They've found them.
Mary: Oh, thank God.
George: Where are they?
Meemaw: Uh, about an hour east of Baton Rouge. Apparently they were on their way to Florida.
Sheldon: That's not where Luke Perry is. Let me speak to them.

Sheldon: [sighs] What was Missy thinking? Why Florida?
Meemaw: Why does it matter?
Sheldon: I made a solid hypothesis backed by data. Where did I go wrong?
Meemaw: You tried to predict a teenage girl.
Sheldon: Perhaps when she gets back we can take her in for a brain scan.
Meemaw: Maybe what Missy needs is for us all to be a little understanding.
Sheldon: I'm trying to understand. That's why I need the brain scan.
Meemaw: Look, your sister's going through a lot these days. She's feeling overlooked, confused, angry, sad.
Sheldon: She's feeling all those things at once?
Meemaw: Yeah.
Sheldon: And I can't scan her brain? That is so unfair.

Adult Sheldon: And I, despite being innocent of all wrongdoing, was being punished as well. Not by my parents, but by society and their insistence on a "spring break."
Sheldon: One whole week of no school. No fair.
Mary: You two should do something together. Go outside, take a walk.
Sheldon: I'd rather die.
Missy: I'd rather read.

Sheldon: Missy, are you busy?
Missy: Do I look busy?
Sheldon: I do some of my best thinking lying down.
Missy: Yeah, well, I'm not thinking.
Sheldon: The shower is another excellent place to cogitate. Sometimes I'll just lather up and drift off...

Sheldon: No, I've watched your program, and I can tell you everything that happened.
Missy: So you know what happens with Brandon's gambling problem? And how Dylan and Kelly are doing?
Sheldon: I do.
Missy: Okay. Wait, why would you do that for me?
Sheldon: Well, when you tried to watch the tape, I ended up watching the first seconds of it, and the completist in me had to finish it.
Missy: That's so dumb. I love it. Tell me everything.

Sheldon: And then she sees Dylan in the hallway and tells her that she and Kelly are friends again, and he kisses her on the forehead.
Missy: What kind of kiss was it?
Sheldon: Well, it seemed innocent, but the music was mysterious, indicating that their love triangle will totally continue.
Missy: Well, that's juicy.
Sheldon: Oh, I'm aware.

Missy: If you want, you can watch with me next week.
Sheldon: No, thank you. Although, I would like to know who killed Dylan's dad.
Missy: Plus, what happened to David's recording contract.
Sheldon: Do you really think he's going to let that producer change his sound?
Missy: Boy, I hope not.
Sheldon: I hear you, sister.

Mary: What are you doing?
Sheldon: Dad and I are watching Star Trek. [George snores] I guess I'm watching Star Trek.
Mary: Want me to watch with you?
Sheldon: Sure. Let me catch you up. The Enterprise is traveling to Eminiar VII to resolve their war with the neighboring Vendikar.
Mary: Uh-huh.
Sheldon: But Kirk suspects that instead of having a real war, the Eminiaries and the Vendikaries are having a computer-simulated conflict.
Mary: Uh-huh.
Sheldon: In Kirk's opinion, by keeping the horrors of war at arm's length, they're simply prolonging it.

Mary: Whew. Sounds like Georgie's home. George, wake up. Watch Star Trek with your son.
George: [exhales] What's happening?
Sheldon: Well, the Enterprise is traveling to Eminiar VII to resolve their war with the neighboring Vendikar. However, Kirk suspects that instead of fighting a real war, the Eminiaries and the Vendikaries are fighting a computer-simulated conflict. Uh-uh. Stay awake.
George: I'm awake.

Sheldon: Dr. Prakash, I'm on the hunt for a mentor who's not afraid to challenge entrenched scientific paradigms.
Dr. Prakash: Well, mainstream science has always been threatened by new ideas.
Sheldon: True. Like Galileo being imprisoned for his heliocentric model of the universe.
Dr. Prakash: And did you know Semmelweis was put in an asylum for suggesting that doctors wash their hands?
Sheldon: I did. Did you know that Michael Servetus discovered pulmonary circulation and was burned at the stake?
Dr. Prakash: Or Henry Oldenburg was arrested...
Sheldon: Arrested as a spy for corresponding with scientists from other countries!
Dr. Prakash: This isn't a competition.
Sheldon: Oh, I thought we were bonding.
Dr. Prakash: Fair enough. We're bonding.

Sheldon: How would you feel about joining me in the groundbreaking search for exoplanets that could support life?
Dr. Prakash: I'd love it. How would you feel about joining me in finding subatomic particles that move backwards in time?
Sheldon: You mean tachyons?
Dr. Prakash: Yes.
Sheldon: That's nonsense. Let's get started on my thing.

Sheldon: [clears throat] You should know, I'm replacing you with a more courageous mentor.
Dr. John Sturgis: I'm sorry to hear that, Sheldon.
[cut to Dr. Linkletter's office:]
Sheldon: One who's not afraid of new ideas.
Dr. Linkletter: Great.
Sheldon: Don't think of it as me walking away, think of it as you being left behind.
Dr. Linkletter: I'm okay with that.
[back to Dr. Sturgis's office:]
Sheldon: Thank you for helping me on my journey. But you're like a rocket booster that must be discarded for me to reach escape velocity.
Dr. John Sturgis: I understand.
[back to Linkletter:]
Sheldon: I'm walking away now.
Dr. Linkletter: Goodbye.
Sheldon: I'm walking backwards, so it seems like you're fading into obscurity.
Dr. Linkletter: Neat.
Sheldon: Take care. Farewell. Ciao.
[back to Sturgis:]
Sheldon: Bon voyage.
Dr. John Sturgis: Arrivederci.
[split-screen:]
Dr. John Sturgis: What a charming young man.
Dr. Linkletter: Kook.

Sheldon: So, where exactly is the telescope?
Dr. Prakash: Hawaii. We just access its data.
Sheldon: Ah. And what are we looking for?
Dr. Prakash: Well, you're looking for these numbers here to change... that would indicate that the star is dimming, possibly because an orbiting planet is passing in front of it.
Sheldon: Mm-hmm. [chuckles softly] ... ... Star Trek made this seem a lot more fun.

Mary: Shelly, how bad could it be? You started college when you were 11.
Sheldon: Well, it was impressive when I was little and cute. But now that I'm old and cute, it's just not the same thing.
Mary: Well, just 'cause you look older, doesn't mean you're any less special.
Sheldon: Of course. It's your fault.
Mary: What?
Sheldon: Well, you've been saying I'm special my whole life, so now I'm conditioned to expect the world to cater to me instead of taking initiative.
Mary: But you are special, sweetie.
Sheldon: You just can't turn it off, can you?

Georgie: I talked to Meemaw. She said if you come back to work at the video store, you can bring the baby. [off Mandy's look] What? I thought you wanted a job.
Mandy: No, I said I wanted a career.
Mary: Oh, are you thinkin' about going back to work already?
Mandy: Yeah. I mean, it's a little earlier than I thought, but an opportunity came up and I'm going for it.
Sheldon: See? Initiative. Her parents kicked her out, and look at that gumption.