Mary: Oh, so, what do we do now?
George Sr.: We don't have a lot of choices. We're gonna be grandparents and, uh... [Mary sighs] What's the girl's name again?
Mary: Mandy.
George Sr.: And Mandy is gonna be part of our lives in some shape or form until we're, you know, dead.
Mary: What do you mean, "shape or form"? Georgie's gotta marry her.
George Sr.: No, Mary, he doesn't.
Mary: How am I supposed to set foot in my church if our son has a child out of wedlock?
George Sr.: It's nobody's business.
Mary: It's a small town, George, everything is everybody's business.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

George Jr.: Okay, in my defense...
Meemaw: You have no defense. You're an idiot.
George Jr.: That was a big part of my defense.

Mary: Maybe it would be better if you went to your parents with, um, good news first.
Mandy: And what would that be?
Mary: Well... everybody loves a wedding.
George Sr.: Would you stop with that?
Mary: It needs to be discussed.
Mandy: No, it doesn't. I'm having a baby, I don't need to marry another one.
George Jr.: I know I'm young now, but think about it... When you're a dried-up old lady, I'll be your hot trophy husband.
Meemaw: Maybe her dad should put you down.

Billy Sparks: You like meatloaf?
Missy: Yeah, is that what we're having?
Billy Sparks: No, just making dinner conversation.