Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Sheldon: And then they laughed at me for not knowing something that they knew. Who does that?
Mary: You do.
Sheldon: Well, this is no time for a teachable moment. Your child is hurting.
Mary: Sorry. [taps Sheldon's shoulder] There, there.
Sheldon: I guess that'll do. Now, how about a hot beverage?

George: And Sheldon's fine. You know what he's like. If someone took him, I'm sure they'll bring him right back.

George: If we take him to a shrink, it feels like we're admitting something's wrong with him.
Mary: He hasn't had solid food in five weeks.
Meemaw: Well, if there is something wrong with him, it ain't constipation.

Missy: Meemaw, are you gonna have any more babies?
Meemaw: Good Lord, no!
Georgie: She's too old to have any more babies.
Meemaw: Don't have to have 'em. You live long enough, your hair and your teeth start falling out, you start wetting the bed, you get to be one.
Georgie: [laughs] That's funny. We're gonna have to put a diaper on you.
Meemaw: You won't be laughing when you're doing it. I might be.