Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Pastor Jeff: And now George's loving wife Mary would like to say a few words. Mary.
Mary: Thank you, Pastor Jeff. Um... [clears throat] I met George in high school. Well, I was in high school. He was an older man with a motorcycle. [light laughter] I'd like to tell you he caught my eye, but actually it was the motorcycle. [laughter] [voice breaking] I'm sorry, I can't... do this. I am... so angry. [sighs] George and I had our ups and downs, but we were finally in such a good place, and then he... left. [crying] He left all of us. I- How could you do that? [Meemaw stands up] I am so mad at him. I'm mad at God, I'm mad at myself for not trying harder while he was here. [Meemaw goes up to Mary] This wasn't supposed to happen. [Mary sobs] [Meemaw hugs Mary] [Georgie hugs a crying Missy]

Sheldon: Do you think Georgie got a tattoo in jail?
Mary: No.
Sheldon: Do you think Meemaw did?
Mary: Probably.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: You smoke marijuana?
Sheldon: Mom!
Libby: No, ma'am.
Tam: Just say no. [Mary shoots him an unimpressed look]

George: Oh.
Georgie: Oh, what?
George: You didn't mention she was black.
Georgie: Was I supposed to?
George: No, 'course not.
Georgie: Then why bring it up?
George: It just wasn't what I was expecting.
Georgie: What were you expecting?
George: It's a big school. Why are you right here?
Georgie: They've got some books in there about Martin Luther King. Maybe you should go read one.

Adult Sheldon: It's called perfect cleavage when gypsum separates this cleanly. I was so proud of Tam for not making an immature cleavage joke.
Tam: Look at me, I'm touching cleavage.
Adult Sheldon: Until he made one.