Mary: I don't understand why you'd even be interested in a book like that.
Sheldon: One of the characters is a scientist who worked on the Manhattan Project.
Mary: Well, it's filled with violence and nudity, and you are done looking at it.
Sheldon: But comics are a form of art. You wouldn't forbid me from looking at Michelangelo's David just because he's nude.
Mary: When a statue of your naked blue fella is on display at the Vatican, we'll talk.
Sheldon: Actually, David is at the Accademia Gallery in Florence.
Mary: Doesn't matter. I don't want you looking at his bottom either.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Pastor Jeff: And now George's loving wife Mary would like to say a few words. Mary.
Mary: Thank you, Pastor Jeff. Um... [clears throat] I met George in high school. Well, I was in high school. He was an older man with a motorcycle. [light laughter] I'd like to tell you he caught my eye, but actually it was the motorcycle. [laughter] [voice breaking] I'm sorry, I can't... do this. I am... so angry. [sighs] George and I had our ups and downs, but we were finally in such a good place, and then he... left. [crying] He left all of us. I- How could you do that? [Meemaw stands up] I am so mad at him. I'm mad at God, I'm mad at myself for not trying harder while he was here. [Meemaw goes up to Mary] This wasn't supposed to happen. [Mary sobs] [Meemaw hugs Mary] [Georgie hugs a crying Missy]

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Georgie: Hey, now that you're treating him like an adult, can I have his allowance?
George: That allowance is for chores, which you already don't do.
Georgie: Come on. We all know I'm your favorite.
Meemaw: You're not even his third favorite.

Adult Sheldon: My new adult responsibilities began that night. Luckily, a cookbook is nothing more than a set of instructions. And if there's one thing I shine at, it's following instructions.

Adult Sheldon: In that moment, I was so angry with her, I almost opened the jar.