Mary: God, please give me the strength to not spread this juicy gossip about Pastor Jeff.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

George Jr.: Thanks for waking me up.
Mary: I woke you up 40 minutes ago.
George Jr.: Well, you didn't do a very good job.

Mary: Well, I am happy to report that my potato salad is once again the hit of the potluck.
George Sr.: That's great, honey.
Mary: I feel bad for Pam Staples. No one's touching her potato salad.
Sheldon: If you feel bad, then why are you smiling?
Meemaw: 'Cause sometimes your mommy's a big ol' hypocrite.

Mary: How are you liking Medford, Selena?
Pastor Jeff: ¿Cómo te gusta Medford?
Selena: Nunca he estado tan aburrido en toda mi vida. [I've never been so bored in my entire life.]
Pastor Jeff: She likes it fine.
Mary: Oh.
Selena: Voy a fumar en el baño. [I'm going to go smoke in the bathroom.]
Pastor Jeff: She needs to use the little girls' room. Mary, could I talk to you for a second?
Mary: Sure.
Pastor Jeff: Don't worry. I'll bring her right back.
George Sr.: Wasn't worried, but okay.
Sheldon: His Spanish is terrible. That's not what she said at all.