Mary: Why doesn't he tell me anything?
George Sr.: When you were a teenager, did you tell your parents stuff?
Mary: Well, no.
George Sr.: Then why do you expect him to?
Mary: 'Cause I'm a cool, fun mom.
George Sr.: [snickers]

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

Sheldon: Dad, the university offered to pay for us to go to California! They're even putting us up in a hotel.
George Sr.: You're kidding.
Missy: We're going to California?
Sheldon: No, just me and Dad.
Missy: That's fair. I'm so happy for you.
Adult Sheldon: Sometimes sarcasm was laid on so thick even I could detect it.
Sheldon: Thanks!
Adult Sheldon: This was not one of those times.

Sheldon: Dad, good news. Airline tickets to California are more affordable than you think.
George Sr.: Sheldon, we're not going.
Mary: What's all this about?
Sheldon: Stephen Hawking is giving a lecture at Caltech. If we leave on Wednesday and are willing to make four layovers, in Boise, Denver, Albuquerque and Fargo, we can get there for only $95 each.

George Sr.: I have a job. I can't just leave in the middle of the week.
Sheldon: Well, then what about Mom?
Mary: Sorry, Shelly, we're not in a position to do this.
Sheldon: But Stephen Hawking's my hero. Imagine if you got a chance to see Jesus or Dad got to meet the man who invented beer.