Mary: I see that. But you understand that your daughter's being abusive to my son.
Brenda Sparks: Well, maybe your son needs to grow a pair.
Mary: And in due time, he will.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

Meemaw: I bowled a new high score last night.
George Sr.: Nice.
Meemaw: I got two turkeys.
Missy: What's a turkey?
Meemaw: It's three strikes in a row.
Missy: Why do they call it a turkey?
Meemaw: Well, when they first invented bowling, they used to just throw frozen turkeys at the pins. Eventually, they switched to balls to cut down on the smell.
George Sr.: Why you lying to her?
Meemaw: I find it keeps my mind sharp.

George Sr.: The little Sparks girl?
Mary: You're kidding. She seems so sweet.
George Jr.: He says she slaps him around, takes his lunch money. She even put a tadpole down his shirt.
Meemaw: Poor kid. He tucks in those shirts.

Adult Sheldon: Existing in a world of predators isn't easy, but we prey have developed several natural defenses to help us survive. There's playing dead, warning calls, camouflage, and, last but certainly not least, good old-fashioned running away. A little screaming never hurts either.