Mary: Did you hear that?
George Sr.: What?
Mary: Sounds like Georgie and Sheldon are getting along.
George Sr.: Really? That can't be right.
Mary: I just heard it.
George Sr.: Maybe there's hope for those two after all.
Mary: Or it's a sign of the apocalypse.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

Sheldon: Do you think a Spock could become a Kirk?
Meemaw: Well, in my experience, most people stay the miserable bastards they are their whole entire life. But I have seen some folks change.

Adult Sheldon: Despite my explanation that I was embracing my inner Kirk, my mother had me make amends for all my misdeeds. Starting in the library, where I had to reshelve hundreds of books. Well, to be honest, that one was a hoot.

Adult Sheldon: The amends got worse when Coach Wilkins made me climb the rope. Lacking any upper body strength, I hung there like a salami in a deli window.