Mary: Didn't Sheldon's college talk to you about coaching there once?
George: That's right, they did.
Mary: And you know the president pretty well now.
George: I do.
Mary: And they're used to losing, so it's low pressure.
George: Thank you.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Oh, I know that you're hurting, and... I'm here for you, so... what do you need?
Meemaw: Great, take me drinking.
Mary: It is 3:30 in the afternoon.
Meemaw: Yes, it's called happy hour.
Mary: I have to make dinner.
Meemaw: Oh, fine. I'll just be sad and drunk by myself. Maybe I'll go home with the bartender.
Mary: Missy! I have to go out with your meemaw, but I'll be back later with KFC.

Adult Sheldon: Today I thought we could talk about relationships, so I've invited my lovely wife Amy to help.
Amy: Thanks for letting me join in.
Adult Sheldon: Are you jealous when I do this without you?
Amy: No.
Adult Sheldon: Because one of the most common sources of conflict in relationships is jealousy. Now, Amy, did you know jealousy is triggered in the left part of the cerebral cortex?
Amy: I'm sorry, are you about to explain neuroscience to your wife, the Nobel Prize-winning neuroscientist?
Adult Sheldon: Yes. Jealous?
Amy: I'll tell you when there isn't a microphone in front of us.
Adult Sheldon: Ooh, mystery. That'll keep a relationship on its toes.
Amy: Your bathroom schedule is on the refrigerator. We have no mystery.
Adult Sheldon: Moving on, physical intimacy. I believe I said "physical intimacy," [title card changes] which can pose another challenge in relationships.
Amy: Especially when one partner doesn't want to be intimate as frequently as the other.
Adult Sheldon: Ooh, who are we talking about? [stammers] Don't tell me. Let the mystery continue.
Amy: Just read the next one.

Adult Sheldon: Money is a frequent source of conflict in a relationship.
Amy: Thankfully that's never been a problem for us.
Adult Sheldon: Says the woman who took away my comic book allowance.
Amy: Uh, to start a college fund for our children.
Adult Sheldon: Comic books are an investment.
Amy: There are better places to invest our money than that weird wolf man you like.
Adult Sheldon: His name is Wolverine and you know it.
Amy: Okay we're off on a tangent. I'm taking over. Money can be a source of conflict in a relationship, even having too much.
Adult Sheldon: Wh... Hey, this is my story.
Amy: I know. Jealous?

Missy: I'm gonna bring a bunch to school.
Georgie: How much you gonna charge for it?
Missy: Nothing. They're my friends.
Georgie: You think Ronald McDonald let his friends eat for free?
Missy: Ronald McDonald isn't real.