Mary: I got to tell you, I'm a little worried about my mother. She keeps betting on these football games, next thing you know, there's an Italian fella driving off with her pickup truck.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Pastor Jeff: And now George's loving wife Mary would like to say a few words. Mary.
Mary: Thank you, Pastor Jeff. Um... [clears throat] I met George in high school. Well, I was in high school. He was an older man with a motorcycle. [light laughter] I'd like to tell you he caught my eye, but actually it was the motorcycle. [laughter] [voice breaking] I'm sorry, I can't... do this. I am... so angry. [sighs] George and I had our ups and downs, but we were finally in such a good place, and then he... left. [crying] He left all of us. I- How could you do that? [Meemaw stands up] I am so mad at him. I'm mad at God, I'm mad at myself for not trying harder while he was here. [Meemaw goes up to Mary] This wasn't supposed to happen. [Mary sobs] [Meemaw hugs Mary] [Georgie hugs a crying Missy]

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Tam: Hey, I've been looking all over for you. Do you know how popular we are?
Sheldon: We?
Tam: Yeah. I put the word out I was helping you with the football stats. And since I'm Asian, they bought it.

Adult Sheldon: In Texas, the Holy Trinity is God, football and barbeque, not necessarily in that order.

Georgie: Fourth down.
George: Gotta punt.
Missy: Gotta.
Sheldon: Statistically, always punting on fourth down makes no sense.
Georgie: Statistically, you're a dumbass.