George: Well, look at that, there's boobies on my TV.
Missy: Ooh!
George: Get out of here!
Missy: I'm telling Mom!

Mary: Missy, if you want a minute with Dad before they close the casket, now's the time. [Missy looks unsure] It's okay if you don't.
Mary: I have to. [Missy stands up and walks up to her father's casket]
[flashback:]
George: Here, let me help you with that. Okay.
Missy: [eats] Holy moly.
George: It's good, huh?
Missy: Unbelievable.
George: I'll leave you to it.
Missy: No, sit with me.
George: Okay.
[present:]
Missy: [crying] Thank you for that. Thank you for everything. [sniffles] I love you.

Sheldon: Is Mom okay?
George: How the heck should I know?
Missy: She left. You can say "hell."

Dr. Sandra Thorpe: Have you always been that way?
Missy: I guess so. I think when you're on your own a lot, you get good at seeing that kind of stuff.
Dr. Sandra Thorpe: Really?
Missy: My dad does football with my older brother, so they're like a team. And my mom and meemaw spend all their time fussing over Sheldon, so they're like a team, too.
Dr. Sandra Thorpe: So no one's on your team?
Missy: Nope. It's just me.

Meemaw: John?
Dr. John Sturgis: Hello.
Meemaw: What- What're you doing?
Dr. John Sturgis: I was doing tai chi and then I realized that I was continually being bombarded by subatomic particles and it behooves me, perhaps, to pay slightly closer attention to them. Maybe "chi" is the ancient Chinese word for the subatomic universe.
Meemaw: You're scaring me, John.
Dr. John Sturgis: Well, there's nothing to be scared of. Tomorrow, somebody will win the Nobel Prize about these particles not me. But I'm experiencing them firsthand [LAUGHS] which could be better.
Meemaw: Why don't you come down and experience them on the floor?
Dr. John Sturgis: I think I just felt a neutrino. [LAUGHING] You know, neutrinos are interesting. They never bond with anything, they're always alone. I think that one went right through my pants.
Meemaw: All right, why don't we go downstairs, and I'll fix us both a nice cup of hot tea and you can tell me all about it. Please?
Dr. John Sturgis: Okay. It was my dream to win the Nobel, and I'm not going to. I bet Sheldon will.
Meemaw: That'll be something.
Dr. John Sturgis: Yeah.

Adult Sheldon: A primary feature of quarks is that they're always bonded together, but in that moment, I felt like a neutrino, destined to be alone forever.
[Montage of young Leonard, Penny, Raj, Howard, Bernadette and Amy at that moment]
Adult Sheldon: Thankfully, I was wrong.

Georgie: A bill? Really?
George: Room and board, buddy.
Georgie: $50 a month for food?
George: The way you eat, I should've gone $50 a week.
Georgie: Laundry services?
George: Your poor mother has to touch your underwear.
Georgie: What's the $10 a month "peema" charge?
George: Oh, P-I-M-A, that's a "Pain in My Ass" tax. My way of getting compensated for you taking years off my life.