Adult Sheldon: Despite his concerns over her sanity, my dad found a rock worthy of her faith garden.
Mary: Ooh, right over there.
Adult Sheldon: [GRUNTS] Here?
Mary: Mm-hmm. [George drops the rock down] Gently!
George Sr.: [PANTING]: Honey, it's a rock.
Mary: I know, but still.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

Mary: Sheldon, faith means believing in something you can't know for sure is real. And right now, I am struggling with that.
Sheldon: So you don't believe in God anymore?
Mary: That isn't something for you to worry about. I need to figure this out myself.
Sheldon: Can I help? Maybe I could provide a fresh perspective.
Mary: I don't think so, baby.
Sheldon: Did you know that if gravity were slightly more powerful, the universe would collapse into a ball?
Mary: I did not.
Sheldon: Also, if gravity were slightly less powerful, the universe would fly apart and there would be no stars or planets.
Mary: Where you going with this, Sheldon?
Sheldon: It's just that gravity is precisely as strong as it needs to be. And if the ratio of the electromagnetic force to the strong force wasn't one percent, life wouldn't exist. What are the odds that would happen all by itself?
Mary: Why are you trying to convince me to believe in God? You don't believe in God.
Sheldon: I don't, but the precision of the universe at least makes it logical to conclude there's a creator.
Mary: Baby, I appreciate what you're trying to do, but logic is here. And my problem is here.
Sheldon: Well, there are 5 billion people on this planet and you're the perfect mom for me. What are the odds of that?

George Jr.: Would you feel more confident if I told you I already know how to drive?
George Sr.: Video games don't count.
George Jr.: I'll have you know I've driven Meemaw's car. I also drove your truck one night while you were sleeping.
George Sr.: Are you crazy?!
George Jr.: I parked it and everything, you had no idea.
George Sr.: Okay, let let me get this straight. You're trying to prove to me that you're a responsible person by admitting you stole my truck.
George Jr.: I said I was responsible, never said I was smart.

Sheldon: And then I said octopus aliens didn't need to become Christian because they're not affected by original sin.
Missy: You should've been there; Pastor Jeff almost started crying.
George Sr.: Oh, now I'm sorry I missed it.
Mary: That's your fault for having a hangover.
George Sr.: Or it's God's fault for putting Sunday morning after Saturday night.