Mary: And bless our appetites, both physical and spiritual, to honor You in all we do. In Jesus' name.
George Jr.: What happened to "Bless the hands that prepared it"?
Mary: I thought I'd mix it up.
George Jr.: I miss the old one.
Missy: Me, too.
George Sr.: Yeah, what I like about the other one-
Mary: And bless the hands that prepared it. Amen.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

Sheldon: I've been corresponding with Dr. John Sturgis at East Texas Tech. He said I could audit his course.
Meemaw: You're pen pals with a stranger? Is this okay?
Sheldon: He's not a stranger. He's a famous scientist. He carbon-dated the oldest human feces.
Meemaw: That ain't strange.

Mary: Now, Shelly, I appreciate that you want to expand your horizons, but how would you even get there? The school's an hour away. I'm working, your dad's working.
George Jr.: Again, who cares? Let him go.
Missy: He could hitchhike.
George Jr.: Perfect.

Meemaw: So, how was everybody's day?
Sheldon: I'm done with high school.
George Sr.: What does that mean?
Sheldon: Well, I don't learn anything there, and I don't want to go anymore.
Mary: Well, where do you think you're gonna go?
George Jr.: Who cares? Let him go.