Mary: I don't like you making me out to be the bad guy just 'cause I won't let my daughter do whatever she wants.
Meemaw: I gave you a lot of freedom, you turned out okay.
Mary: You didn't give me freedom. You were never around.
Meemaw: Is that so?
Mary: I guarantee I made supper for Charlene and Edward more times than you ever did. I basically raised 'em.
Meemaw: You think I was out dancing? I was out working two jobs so your daddy could lose all our money on that damn chain of Fotomats!
Mary: It wasn't Daddy's fault that those little things blew over every time there was a storm.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Pastor Jeff: And now George's loving wife Mary would like to say a few words. Mary.
Mary: Thank you, Pastor Jeff. Um... [clears throat] I met George in high school. Well, I was in high school. He was an older man with a motorcycle. [light laughter] I'd like to tell you he caught my eye, but actually it was the motorcycle. [laughter] [voice breaking] I'm sorry, I can't... do this. I am... so angry. [sighs] George and I had our ups and downs, but we were finally in such a good place, and then he... left. [crying] He left all of us. I- How could you do that? [Meemaw stands up] I am so mad at him. I'm mad at God, I'm mad at myself for not trying harder while he was here. [Meemaw goes up to Mary] This wasn't supposed to happen. [Mary sobs] [Meemaw hugs Mary] [Georgie hugs a crying Missy]

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Adult Sheldon: I didn't realize until years later that my father was only asking questions about lightning and thunder to cheer me up. In fact, he would often pretend to be dumb just to make me feel better.

Adult Sheldon: I never did get to see a launch in person, but that was the best trip I ever had. I wish I had told my father while he was alive.

Mary: Wait, Georgie. Where's your bag?
Georgie: Don't need one. Got my toothbrush right here.
Mary: What about clothes? A change of underwear?
Georgie: Got it.
Mary: Georgie, you're gonna be gone for two days.
Georgie: I'll turn them inside out.