Mary: How was your day?
George Sr.: Awful.
Mary: Oh. Well... I have good news.
George Sr.: I could use it.
Mary: I got a job at the bowling alley.
George Sr.: [gulps] Working with Brenda?
Mary: Every day. [phone rings]
George Sr.: That is... really... really good news.
Mary: Mm-hmm.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

Adult Sheldon: My sister encouraged me to embrace adolescence as a journey of scientific discovery. I stood before a whole new teenage world of music, slang words and even clothing styles. [Sheldon removes a red Flash t-shirt] Pretty groovy, huh?
[Sheldon stands in front of his bedroom mirror wearing the red Flash t-shirt over a blue undershirt]
Sheldon: Wow, I might look too cool.

Adult Sheldon: [hushed] This is why the only bar I frequent is the Genius Bar at the Apple Store.

President Hagemeyer: Okay, so, what's the problem?
Sheldon: I wanted to talk with Dr. Linkletter about puberty.
Dr. Linkletter: And I wanted to avoid litigation.