George: Everything okay?
Missy: No.
George: What's wrong?
Missy: Everyone's parents are upset about the sex talk Mom wants to give, and all my friends are all blaming me.
George: What? This wasn't your fault.
Missy: That didn't stop Marjorie Jones from taking my seat at the lunch table, and I also got uninvited from two birthday parties.
Sheldon: That's silly. All you did was ask questions.
Missy: And it's ruining my life. I'm never talking about sex ever again.
George: Well, all right.

Mary: Missy, if you want a minute with Dad before they close the casket, now's the time. [Missy looks unsure] It's okay if you don't.
Mary: I have to. [Missy stands up and walks up to her father's casket]
[flashback:]
George: Here, let me help you with that. Okay.
Missy: [eats] Holy moly.
George: It's good, huh?
Missy: Unbelievable.
George: I'll leave you to it.
Missy: No, sit with me.
George: Okay.
[present:]
Missy: [crying] Thank you for that. Thank you for everything. [sniffles] I love you.

Sheldon: Is Mom okay?
George: How the heck should I know?
Missy: She left. You can say "hell."

Sheldon: While Dad's gone, I'm the man of the house, and the man of the house has to enforce the rules.
Missy: The man of the house is about to get his teeth knocked out.
Sheldon: Puberty's made you mean.
Missy: I need to know what happened on my show.
Sheldon: And you'll find out when your privileges are restored.
Missy: I can't wait that long, each episode builds on the last. Imagine a Star Trek that ends with "to be continued," and you don't get to continue.
Sheldon: That would never happen, because I follow the rules.
Missy: You are this close to a purple nurple.
Sheldon: [covers nipples] You leave my nurples alone.

Meemaw: I'll tell you what, we're in the gambling business, why don't we gamble for it?
Georgie: Okay.
Meemaw: Great. The number I'm thinking of in my head... is it odd or even?
Georgie: How dumb do you think I am?
Meemaw: In my defense, you used to be dumber.

Sheldon: [knocks on door] Missy, I know you're upset. Would you like a hot beverage?
Missy: [o.s.] Go away.
Adult Sheldon: Every culture has their taboos. In the Ukraine, it's rude to whistle indoors, and they're correct. Not a fan. In our society, any discussion of human reproduction seems to be so upsetting, it causes nothing but chaos. Lost jobs. Lost friends. Sleepless nights. Even the word "sex" provokes an uncomfortable reaction. I thought "fornicate" might work, but that seemed too judgy. Then I found the perfect word, a word so bland and clinical that it would be impossible to take offense to it.
Sheldon: "Coitus." That'll work.

Pastor Rob: I'm thinking it might be a good idea if we gave the kids a talk about the facts of life.
Pastor Jeff: You mean like, S-E-X?
Peg: Who are you spelling that for?
Pastor Jeff: G-O-D.