Mary: I understand that you want to be appreciated for what you do, but so do I. This is my home and taking care of my family is the choice that I've made, and I am proud to do it.
Sam: Okay.
Mary: It is okay. And I am sorry if me baking cookies says something bad about women, but if you think that Sheldon is difficult to work with now, you should try him with low blood sugar, he is a monster.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Pastor Jeff: And now George's loving wife Mary would like to say a few words. Mary.
Mary: Thank you, Pastor Jeff. Um... [clears throat] I met George in high school. Well, I was in high school. He was an older man with a motorcycle. [light laughter] I'd like to tell you he caught my eye, but actually it was the motorcycle. [laughter] [voice breaking] I'm sorry, I can't... do this. I am... so angry. [sighs] George and I had our ups and downs, but we were finally in such a good place, and then he... left. [crying] He left all of us. I- How could you do that? [Meemaw stands up] I am so mad at him. I'm mad at God, I'm mad at myself for not trying harder while he was here. [Meemaw goes up to Mary] This wasn't supposed to happen. [Mary sobs] [Meemaw hugs Mary] [Georgie hugs a crying Missy]

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Meemaw: All right, come on, let's talk about something else.
June: Okay.
Dr. John Sturgis: A lot of people here like to talk about the game.
Meemaw: Really? You speak sports now?
Dr. John Sturgis: I sure do. Check this out. Hey, ref! I suggest you go back to referee school and this time pay attention in class!
Man #1: You tell him, Doc.

Georgie: Ready to go?
Missy: Yep.
Mary: Go where?
Missy: The mall.
Mary: What happened to asking for permission?
Missy: I asked Dad.
Mary: You know that doesn't count.
Missy: That's what he said.

Keith: How about we work in my dorm tomorrow?
Mary: Um, I don't know if a dormitory is the right environment for someone his age.
Sheldon: If you're worried about the beer-drinking, Dad has thoroughly desensitized me.