Mary: I brought you some coffee.
Sam: You don't have to keep waiting on us.
Mary: I'm sorry, is there a problem?
Sam: I'm just frustrated.
Mary: Is it Sheldon?
Sam: It's Sheldon and Keith and every other guy in our field, which is basically everyone. There were only three other women and one of them just dropped out to get married.
Mary: Oh, good for her. O-Or bad, bad for science, bad for women.
Sam: None of the guys in my class take me seriously, and honestly, it doesn't help when women like you run around doing their laundry and making them snacks.
Mary: I'm just being a good host.
Sam: Yeah, and raising another boy to think that all women are just notetakers and mommies.
Mary: I'm sorry I'm making life so hard for you. And for your information, Sheldon does not look down on women, he looks down on everyone.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Oh, I know that you're hurting, and... I'm here for you, so... what do you need?
Meemaw: Great, take me drinking.
Mary: It is 3:30 in the afternoon.
Meemaw: Yes, it's called happy hour.
Mary: I have to make dinner.
Meemaw: Oh, fine. I'll just be sad and drunk by myself. Maybe I'll go home with the bartender.
Mary: Missy! I have to go out with your meemaw, but I'll be back later with KFC.

Meemaw: All right, come on, let's talk about something else.
June: Okay.
Dr. John Sturgis: A lot of people here like to talk about the game.
Meemaw: Really? You speak sports now?
Dr. John Sturgis: I sure do. Check this out. Hey, ref! I suggest you go back to referee school and this time pay attention in class!
Man #1: You tell him, Doc.

Mary: How about you all come work at our house?
Sam: I guess if that's our only option.
Mary: It'll be fun. I'll make food. You can even bring your laundry.
Keith: That actually would be great.
Sheldon: Now this man's soiled underpants will be in my kitchen. Thank you.

Keith: How about we work in my dorm tomorrow?
Mary: Um, I don't know if a dormitory is the right environment for someone his age.
Sheldon: If you're worried about the beer-drinking, Dad has thoroughly desensitized me.