Mary: I brought you some coffee.
Sam: You don't have to keep waiting on us.
Mary: I'm sorry, is there a problem?
Sam: I'm just frustrated.
Mary: Is it Sheldon?
Sam: It's Sheldon and Keith and every other guy in our field, which is basically everyone. There were only three other women and one of them just dropped out to get married.
Mary: Oh, good for her. O-Or bad, bad for science, bad for women.
Sam: None of the guys in my class take me seriously, and honestly, it doesn't help when women like you run around doing their laundry and making them snacks.
Mary: I'm just being a good host.
Sam: Yeah, and raising another boy to think that all women are just notetakers and mommies.
Mary: I'm sorry I'm making life so hard for you. And for your information, Sheldon does not look down on women, he looks down on everyone.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Pastor Jeff: And now George's loving wife Mary would like to say a few words. Mary.
Mary: Thank you, Pastor Jeff. Um... [clears throat] I met George in high school. Well, I was in high school. He was an older man with a motorcycle. [light laughter] I'd like to tell you he caught my eye, but actually it was the motorcycle. [laughter] [voice breaking] I'm sorry, I can't... do this. I am... so angry. [sighs] George and I had our ups and downs, but we were finally in such a good place, and then he... left. [crying] He left all of us. I- How could you do that? [Meemaw stands up] I am so mad at him. I'm mad at God, I'm mad at myself for not trying harder while he was here. [Meemaw goes up to Mary] This wasn't supposed to happen. [Mary sobs] [Meemaw hugs Mary] [Georgie hugs a crying Missy]

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Meemaw: All right, come on, let's talk about something else.
June: Okay.
Dr. John Sturgis: A lot of people here like to talk about the game.
Meemaw: Really? You speak sports now?
Dr. John Sturgis: I sure do. Check this out. Hey, ref! I suggest you go back to referee school and this time pay attention in class!
Man #1: You tell him, Doc.

Georgie: Ready to go?
Missy: Yep.
Mary: Go where?
Missy: The mall.
Mary: What happened to asking for permission?
Missy: I asked Dad.
Mary: You know that doesn't count.
Missy: That's what he said.

Keith: How about we work in my dorm tomorrow?
Mary: Um, I don't know if a dormitory is the right environment for someone his age.
Sheldon: If you're worried about the beer-drinking, Dad has thoroughly desensitized me.