Meemaw: Come here. I want to show you something. [leading Mary into the bathroom] Look at this. John did it. [pulling back the shower curtain to reveal an equation scribbled on the wall]
Mary: Oh, dear.
Meemaw: "Oh, dear" is right.
Mary: Was he in here taking a bath and just started thinking about science stuff?
Meemaw: Read the top right part.
Mary: "Time plus heat plus bread equals toast."
Meemaw: [whispering] That ain't science.
Mary: Well, it's not wrong, either.
Meemaw: Look at this.
Mary: Yeah, well, that's peculiar.

Georgie: Hey, now that you're treating him like an adult, can I have his allowance?
George: That allowance is for chores, which you already don't do.
Georgie: Come on. We all know I'm your favorite.
Meemaw: You're not even his third favorite.

Mary: Mom, can you make the salad?
Meemaw: Sure.
George: Hey, don't put in any of those little tomatoes.
Meemaw: Hey, I don't tell you how to impersonate a lump of clay. You don't tell me how to make a salad.

Sheldon: Do people know about this?
Meemaw: Sheldon, what's on a person's face is not always what's in their heart.
Sheldon: Well, this changes everything. How do you know who to trust?
Meemaw: You don't. That's what makes life interesting.

Adult Sheldon: A primary feature of quarks is that they're always bonded together, but in that moment, I felt like a neutrino, destined to be alone forever.
[Montage of young Leonard, Penny, Raj, Howard, Bernadette and Amy at that moment]
Adult Sheldon: Thankfully, I was wrong.

Meemaw: John?
Dr. John Sturgis: Hello.
Meemaw: What- What're you doing?
Dr. John Sturgis: I was doing tai chi and then I realized that I was continually being bombarded by subatomic particles and it behooves me, perhaps, to pay slightly closer attention to them. Maybe "chi" is the ancient Chinese word for the subatomic universe.
Meemaw: You're scaring me, John.
Dr. John Sturgis: Well, there's nothing to be scared of. Tomorrow, somebody will win the Nobel Prize about these particles not me. But I'm experiencing them firsthand [LAUGHS] which could be better.
Meemaw: Why don't you come down and experience them on the floor?
Dr. John Sturgis: I think I just felt a neutrino. [LAUGHING] You know, neutrinos are interesting. They never bond with anything, they're always alone. I think that one went right through my pants.
Meemaw: All right, why don't we go downstairs, and I'll fix us both a nice cup of hot tea and you can tell me all about it. Please?
Dr. John Sturgis: Okay. It was my dream to win the Nobel, and I'm not going to. I bet Sheldon will.
Meemaw: That'll be something.
Dr. John Sturgis: Yeah.

Georgie: A bill? Really?
George: Room and board, buddy.
Georgie: $50 a month for food?
George: The way you eat, I should've gone $50 a week.
Georgie: Laundry services?
George: Your poor mother has to touch your underwear.
Georgie: What's the $10 a month "peema" charge?
George: Oh, P-I-M-A, that's a "Pain in My Ass" tax. My way of getting compensated for you taking years off my life.