Mary: Hi, Mom. Kids okay?
Meemaw: Yeah, they're fine. How's George?
Mary: I don't know. They're running tests.
Meemaw: Well, don't you worry about us. Everything's under control here.
Mary: Okay. I'll call you when I know more.
Meemaw: How you holdin' up?
Mary: I guess I'm okay.
Meemaw: Well, George is gonna pull through this, honey. I guarantee it.
Mary: Thanks, Mom. Thanks for bein' there.
Meemaw: You bet.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

Sheldon: Do people know about this?
Meemaw: Sheldon, what's on a person's face is not always what's in their heart.
Sheldon: Well, this changes everything. How do you know who to trust?
Meemaw: You don't. That's what makes life interesting.

Adult Sheldon: I've often been asked why I never learned to drive a car. This night is your answer.

Adult Sheldon: But I wasn't a good sport. At that moment, I vowed to come back the following Sunday and destroy Pastor Jeff.