Mary: We're going to support your brother. Not another word about it.
George Sr.: Can we at least sit in the back?
Mary: Not a word.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

George Sr.: You don't always win in life, he needs to learn that.
Mary: I know, but these are big feelings for a little boy.
George Sr.: They're feelings everybody has. It's part of growing up.
Mary: I guess.
Sheldon: Poodle poop!
Meemaw: Okay. Somebody's got to teach this kid to swear, it's embarrassing.

Principal Petersen: And the winner of the Medford High School Science Fair is SueAnn Ludlow!
Sheldon: You've got to be kidding me!
Mary: Shelly.
Sheldon: You people are crazy!
George Sr.: Hey. All right.
Sheldon: You're celebrating mediocrity. Mediocrity! Mediocrity!

Missy: I think I see his underpants.
Meemaw: I told you. Theatre folk just love to show off their business.