Mary: I know that I'm not winning any popularity contests, but I'm gonna do whatever it takes to make sure that my kids are safe. In this life and the next.
Meemaw: Damn. I really thought I was gonna bring ya around.
Mary: I'm on my game today. Sheldon said so.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Sheldon: And then they laughed at me for not knowing something that they knew. Who does that?
Mary: You do.
Sheldon: Well, this is no time for a teachable moment. Your child is hurting.
Mary: Sorry. [taps Sheldon's shoulder] There, there.
Sheldon: I guess that'll do. Now, how about a hot beverage?

[Adult Sheldon walks through his childhood home:]
Adult Sheldon: Eventually, my mom sold the house. My dad's chair was gone. My spot was gone. [sits down on couch] Where we ate together. But I can still remember it exactly the way it was the day I left for Caltech.
Missy: Hey.
[Young Sheldon turns around to face Missy]
Missy: What are you doing?
Sheldon: Taking it all in one last time, so I remember it when I'm older.
Missy: You gonna remember me?
Sheldon: I have an eidetic memory. I have no choice.
Missy: Ha.

Mary: Are you gonna go, too? I know you don't believe.
Sheldon: I don't. But I believe in you.
Mary: Thank you.

Pastor Jeff: Okay, now our next baptism is for Sheldon Lee Cooper, our soon-to-be brother in Christ. And, personally, this is a big get for me.