Mary: I thought you were with Missy.
Meemaw: Oh. I thought it was a good idea if she talked to Mandy. They're closer in age.
Mary: She threw you over, didn't she?
Meemaw: Without hesitation.
Mary: Stings, don't it?
Meemaw: It do.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

Meemaw: How about this... Why don't you get one of your girlfriends to find out how he feels about you.
Missy: Why?
Meemaw: Because then you don't have to put yourself on the spot.
Missy: Okay. And if he doesn't like me back, I'll just keep being mean to him until he does.
Meemaw: I don't know why that works. Men are dumb.
Missy: Does that mean we're dumb for liking 'em?
Meemaw: It's not a good look for us.

Sheldon: Okay, your basic arithmetic skills are disappointing but functional.
Billy Sparks: Thank you.
Sheldon: All right, let's talk about negative numbers.
Billy Sparks: I'm all ear.
Sheldon: "Ears."
Billy Sparks: No. "Ear." This one's clogged.

Sheldon: All right, I'm given to understand you have a test coming up on negative numbers and fractions.
Billy Sparks: Yeah.
Sheldon: So, what part don't you understand? [Billy is silent] Oh, boy. Let's take it back a step. Where do you stand on addition, subtraction, multiplication and division?
Billy Sparks: I'm against it.
Sheldon: [exhales] [quietly] Oh, boy.