Missy: [answers phone] Hello? Sheldon, it's for you.
Sheldon: Who is it?
Missy: Who is it? Travis.
George Sr.: Who's Travis?
Missy: Who are you? Friend of Sheldon's.
George Sr.: Really?
Missy: Really?

Missy: So, this Dr. Lee is turning your friends against you?
Sheldon: Essentially.
Missy: Classic move. Most girls you find crying in the school bathroom, that was it.
Sheldon: What do I do?
Missy: Well, you're in a tough spot 'cause your personality is ugh.
Sheldon: There's enough people being mean to me right now.
Missy: Sorry.
Sheldon: Can you help me or not?
Missy: It's you against a bunch of college professors. I don't think you can win this one. [Sheldon starts to walk away] Oh. Do any of them have pimples?
Sheldon: No.
Missy: Too bad, I've done a lot of damage with "pizza face."

George Sr.: What are you doing?
Missy: Watching Sheldon struggle with homework. It's so great.

Mary: Bless us, Lord, for the food we are about to receive and bless the hands that prepared it.
Missy: And bless Mom.
Mary: Thank you. Amen.
Missy: Amen.
George Jr.: Amen.
Sheldon: She's the hands that prepared it. Your blessing is redundant.
Mary: Let's eat.

Sam: This is so unfair. You get so much more than every other student.
Sheldon: Fair isn't everyone getting the same thing. Fair is everyone getting what they deserve.
Sam: Sheldon, that arrogant attitude is why no one sits with you in class or lunch or ever.
Sheldon: Well, I like to think that they're maintaining a respectful distance out of deference to my intellect.
Sam: No. That's not what they're doing. They're avoiding you because you're an entitled brat who thinks that you're better than everybody else.
Sheldon: So, I should just pretend I'm less intelligent than I am?
Sam: You should realize that there are more important things in life than how smart you are.
Sheldon: Well, I'm also cute as a button, but it seems shallow to say it. [an exasperated Sam walks away] You could say it.

Dr. John Sturgis: You see, humans have evolved as social animals, so your feeling hurt might be a deep evolutionary desire to cooperate with others to ensure your survival.
Sheldon: So, you're saying it makes sociobiological sense to want other people to like me?
Dr. John Sturgis: Yes, and you may even get benefits from it. It's like on that show you enjoy, Star Track.
Sheldon: Trek.
Dr. John Sturgis: Right. Captain Kirk can't do it all by himself. He needs Doctor Spock.
Sheldon: Mister.
Dr. John Sturgis: Right. And Mister McCoy.
Sheldon: Doctor.
Dr. John Sturgis: Right.
Sheldon: Well, technically, they were his subordinate officers, but Kirk did always deal with them in a friendly manner, so I take your point.
Dr. John Sturgis: Good man.
Sheldon: I suppose I could treat it like an experiment. Run an analysis of the benefits of having people like me.
Dr. John Sturgis: That sounds like an idea the Captain, the Doctor, or the Mister would be proud of.
Sheldon: Excellent.
Dr. John Sturgis: You know, you'd think a smart fella like Spock would have a doctorate.
Sheldon: Actually, Spock rejected an offer from the Vulcan Science Academy in order to attend Starfleet.
Dr. John Sturgis: Huh. Not the choice I would have made, but I'm happy for him.

President Hagemeyer: Here we are.
Sheldon: [chuckles] What is this?
President Hagemeyer: A dorm room, and it's all yours. You can study, take naps, do whatever you want.
Sheldon: No one's living here?
President Hagemeyer: Well, we had an Indian exchange student, but he developed a taste for barbecue, so his parents made him go home.
Sheldon: Well, thank you for this.
President Hagemeyer: You're welcome.
Sheldon: It's like I always say, never underestimate the power of complaining.
Adult Sheldon: I've been testing that theory for decades, still works like gangbusters.