Alex Trebek: [on TV] Animated films. Frog anatomy. The Bible.
Missy: Why are you watching Jeopardy?
George Sr.: Sheldon's not the only one who likes to learn stuff.
Missy: You don't know where the remote is.
George Sr.: It's right here. It's just out of batteries.
Missy: Want me to get some?
George Sr.: A can of beer while you're up.

George Sr.: And Sheldon's fine. You know what he's like. If someone took him, I'm sure they'll bring him right back.

Sheldon: Dad, do you believe that fossils are millions of years old?
George Sr.: I guess. Why?
Sheldon: Well, Mom believes the world was only created 6,000 years ago.
George Sr.: Yeah. So?
Sheldon: Are these differences a sticking point in your marriage?
George Sr.: Not at all.
Sheldon: Why?
George Sr.: Simple. We never talk about it.
Sheldon: So you just avoid discussing topics you don't agree on?
George Sr.: At all costs.

Meemaw: I bowled a new high score last night.
George Sr.: Nice.
Meemaw: I got two turkeys.
Missy: What's a turkey?
Meemaw: It's three strikes in a row.
Missy: Why do they call it a turkey?
Meemaw: Well, when they first invented bowling, they used to just throw frozen turkeys at the pins. Eventually, they switched to balls to cut down on the smell.
George Sr.: Why you lying to her?
Meemaw: I find it keeps my mind sharp.

Mary: [prays] Please watch over Missy and Sheldon and especially Georgie. And please don't let my failings as a mother get in the way of Your plans for their lives. Amen. [gasps] Hey, baby. What's wrong?
Sheldon: Is it that obvious?
Mary: Well, you are outside, where birds live.
Sheldon: True. I'll make it quick. I'm experiencing what the Germans call weltschmerz.
Mary: Uh-huh. And what do Americans call it?
Sheldon: The pain of the world.
Mary: Sounds more fun in German.
Sheldon: Most things do.

Mary: You are unbelievable. It is bad enough for you to do all this stuff, but then to drag Georgie down into your den of sin.
Meemaw: Oh, please, it's not a den of sin. Although that is a great name. Den of Sin. That would get some butts in seats. [Mary exclaims]

Pastor Jeff: Hey, Mary. Quick question. Why can I see you through my newsletter?
Mary: Oh, sorry, I had to remove one of the ads.
Pastor Jeff: Was there anything important on the other side?
Mary: Just Peg's recipe for her grape salad.
Pastor Jeff: With the mayonnaise and the pretzels. Barf.