Sheldon: I can't believe they would fire you just for mentioning a theory about black holes.
Dr. John Sturgis: It's just as well. It was time this old horse was put out to pasture.
Mary: Don't say that. You're not old.
Missy: He's not?
Mary: No.
Missy: But look at his bald head.
Mary: Eat your peas.

Sheldon: While Dad's gone, I'm the man of the house, and the man of the house has to enforce the rules.
Missy: The man of the house is about to get his teeth knocked out.
Sheldon: Puberty's made you mean.
Missy: I need to know what happened on my show.
Sheldon: And you'll find out when your privileges are restored.
Missy: I can't wait that long, each episode builds on the last. Imagine a Star Trek that ends with "to be continued," and you don't get to continue.
Sheldon: That would never happen, because I follow the rules.
Missy: You are this close to a purple nurple.
Sheldon: [covers nipples] You leave my nurples alone.

Missy: I'm totally into old movies. You know, Breakfast Club, Goonies, Pretty in Pink.

Missy: One question.
George: Yes?
Missy: What's 0600?

Adult Sheldon: [v.o.] We often regret the things we don't say. There's a lot of things I wish I had said to my dad while he was around. That I appreciated him. That I loved him. Which is why I'm grateful for the times I did tell him how I felt.
Sheldon: Tonight was fun.
George: Yeah? Why is that?
Sheldon: Dr. Sturgis was here. Everybody talked about science. It was nice.
George: It was.

President Hagemeyer: Sheldon, Dr. Sturgis quit right before the semester started. He left me in the lurch.
Sheldon: And this is your chance to be the bigger person.
President Hagemeyer: I don't want to be the bigger person. I'll be the small, petty person. That's way more fun.
Sheldon: Please? It would make me really happy if he came back. And you said yourself my happiness is important to the university.
President Hagemeyer: Are you trying to manipulate me?
Sheldon: Hey, being small and petty is fun.

Meemaw: Thanks for inviting John to dinner tonight.
Mary: Oh, my pleasure.
Meemaw: I've been a little bit worried about him. You know, with what happened last time.
Mary: At least he didn't seem unstable when I talked to him.
Meemaw: The man has a doctorate in science, and he's filling people's grocery bags.
Mary: He actually did a really nice job. He put the heavy things on the bottom. He kept the cold things together.
Meemaw: Mary.
Mary: Well, they don't always do that.