Sheldon: Ooh, there's a computer game called Railroad Kingdom. Can we get it?
Mary: How much is it?
Sheldon: $49.95.
Missy: Are you crazy?
Mary: I'll handle this. I am not paying that much for a game.
Sheldon: It's not just a game. It's a cutting-edge simulation teaching business skills in the golden age of railroads.
Mary: It doesn't matter.
Sheldon: But what if I end up running a railroad one day and don't have the necessary business skills?
Missy: I think I nailed it with, "Are you crazy?"

Mary: Let's say grace.
Sheldon: Hang on, safety first. [puts mittens on]
George Jr.: When are you gonna get over that?
Sheldon: I would think recent events would make you value protection.
Mary: Enough.

Ms. MacElroy: Now, can anyone tell me why Melville shifts the narrative voice from Ishmael to Ahab? [Ms. MacElroy waits for somebody else to raise their hand] Sheldon.
Sheldon: I have a tummyache. I'd like to see the nurse.
Derek: A "tummyache"?
Sheldon: Yes, Derek, I have a tummy and it aches. Ergo, tummyache.
Derek: Ergo?
Sheldon: It's Latin, Derek.
Ms. MacElroy: Go to the nurse.
Sheldon: And to answer your question, the shifting point of view grants the reader a broader perspective of events than typically allowed by first-person narration.
Ms. MacElroy: Where were we?
Sheldon: And "ergo" is Latin for "hence," Derek.

Missy: What's it like to not believe in God?
Sheldon: It's great. Big fan.
Missy: Are you ever afraid you're wrong?
Sheldon: About religion? Never. About other things? Also never.

Adult Sheldon: Like a virus, heartbreak can also spread. Once it does, it's hard to contain. In some cases you can try to reboot and start over. But it makes you appreciate those early days, when your hard drive was clean... and the world was full of possibility.

Meemaw: Well, let's get into it. What happened? If it's another woman, she's a tramp, and you're way prettier.
Brenda Sparks: No. Although sometimes I wish there was. Then I'd have someone to be mad at other than myself.
Meemaw: And here I thought this one was gonna be the sad sack.
Mary: Mom, that is enough.
Meemaw: Oh, there's my little killjoy. [both laughing]

Adult Sheldon: As long as humans have been on Earth, they've had to contend with viruses. And as long as I've been on Earth, I've come up with fun ways to avoid them.
[flashback:]
Dr. Linkletter: I've heard so much about you. [offers hand]
Sheldon: Apparently not how I feel about shaking hands.
Adult Sheldon: I wear personal protective equipment...
[flashback to Sheldon putting on mittens at the dinner table]
[flashback to Sheldon wearing an astronaut suit in his bubble:]
Mary: You come here right this instant.
Adult Sheldon: ...and I was social distancing before it was cool. But in the early '90s, a new type of virus became prevalent. One that no amount of hand-washing could stop. A computer virus.
Sheldon: Oh, no.
Adult Sheldon: But let's back up and begin this story in a simpler time, before an insidious infection had upended my life.