Pastor Jeff: Two months! Two months till this baby comes! There's so much I thought I was gonna do in my life.
George: I'm sure you've done plenty.
Pastor Jeff: Nothing cool. Look at you. You played football and rode a motorcycle.
George: Well, you save people's souls. That's neat, right?
Pastor Jeff: Oh, it's neat as neat can be, but you know that's not what I'm talking about.
George: [sighs] Look, being a dad doesn't mean your life is over. It just means it's different. Instead of playing football, I get to coach it now. I mean, high school football. Not college like I'd hoped. I-Instead of a motorcycle, I drive a truck. To work every single day. To pay the bills. [sighs] Oh. Endless bills. What happened to my life?
Pastor Jeff: Orange wedge?

George: And Sheldon's fine. You know what he's like. If someone took him, I'm sure they'll bring him right back.

Sheldon: There's going to be a lecture on carbon dating at the Natural Science Museum on Saturday. Who would like to take me?
George: You know what? I'd be happy to.
Meemaw: What happened to helping me at my yard sale?
George: Ooh, is that this Saturday? I'm sorry. I'm taking him to a lecture on, uh what is it? Carbonation?
Sheldon: Carbon dating. A method of determining the age of artifacts and fossils.
George: Hey, we could use that to figure out how old your grandma is.
Sheldon: That won't work. You can't carbon-date something that's alive.
George: Well, then, we'll just chop her down and count the rings.
Meemaw: Oh, George, did my "lump of clay" remark strike a nerve?
George: A little.

Georgie: A bill? Really?
George: Room and board, buddy.
Georgie: $50 a month for food?
George: The way you eat, I should've gone $50 a week.
Georgie: Laundry services?
George: Your poor mother has to touch your underwear.
Georgie: What's the $10 a month "peema" charge?
George: Oh, P-I-M-A, that's a "Pain in My Ass" tax. My way of getting compensated for you taking years off my life.

Billy Sparks: Who's Melissa?
Missy: Me.
Billy Sparks: Then who's Missy?
Missy: "Missy" is short for "Melissa." Like how "Billy" is short for "William."
Billy Sparks: I don't understand.
Missy: You know how your real name is William?
Billy Sparks: I'm Billy.
Sheldon: No, we call you Billy, but your real name is William.
Billy Sparks: But my underpants say "Billy" in them. Mom, is my name William?
Brenda Sparks: [sighs] Yeah.
Billy Sparks: Then whose underpants am I wearing?

Dr. John Sturgis: [v.o.] Dear Connie, you may have heard I've taken a job at the new supercollider in Waxahachie. I wanted to tell you in person, but, uh, I was afraid you'd be upset. And, honestly... I was even more afraid you wouldn't be.
Meemaw: Oh, John.
Dr. John Sturgis: This also gives me an excuse to use my astronaut pen. I'm not upside-down, but if I was, it would still write. [laughs]

Sheldon: I may not look it, but I'm the future of physics, so just move on.