Brenda Sparks: [on the phone] Listen, I'm just doing you a favor. The other moms on the team are starting to talk.
Mary: Well, maybe the other moms need to mind their own business.
Brenda Sparks: Come on, Mary. Isn't one weird kid in your family enough? You going for a record?
Mary: [hanging up] You're playing baseball.
Missy: But you said it was my decision.
Mary: It is. And you're playing.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Mary: Sheldon Lee Cooper, if you don't finish that pork chop, I swear I will chew it up and spit it in your mouth like a mama bird.
Missy: Do it, Mom. Do it.

Adult Sheldon: Thanks to Dr. Sturgis, I had all the intellectual ammunition I needed to bring my opponent to his knees. I accused him of conflating two different interpretations of quantum theory, woefully misrepresenting Paul Dirac, and when I called him a dung beetle in Latin, I was so riled up, I almost started producing testosterone.

Lisa: [modem screeching] What's that noise?
George Jr.: No idea.
Sheldon: Georgie, I need you to get off the phone.
George Jr.: Hang on, Lisa. I'm helping someone with their English homework.
Sheldon: I don't have time for jokes. I need the phone line to connect my modem.
George Jr.: What the hell's a modem?
Sheldon: It links my computer to an interconnected web of other computers in order to facilitate the exchange of ideas.
George Jr.: That's the stupidest thing I've ever heard of.
Adult Sheldon: Sadly, that was not the stupidest thing he ever said.

Dale: Hey, Billy! You're supposed to be warming up.
Billy Sparks: I found a worm!