Sheldon: I could offer an assortment of breakfast cereal.
Tam: My mom doesn't let me have cereal with sugar in it. Or anything that makes me happy.

Mary: You smoke marijuana?
Sheldon: Mom!
Libby: No, ma'am.
Tam: Just say no. [Mary shoots him an unimpressed look]

Tam: Spending the Thanksgiving weekend working in my family's convenience store, I observed my father and mother working from 6:00 in the morning till 10:00 at night. My hypothesis was that economic advancement for immigrant families is more important than celebrating a holiday where people eat until they pass out in front of the TV.
Mr. Givens: All right, Tam. Well, based on your observations and hypothesis, were you able to make a prediction?
Tam: Yes. At some point, my father would die prematurely from stress. And my mother will come live with me, where she will constantly disapprove of my hot, blonde, American wife.
Mr. Givens: Okay. Uh, I think we all learned something there. Uh, thank you, Tam.

Tam: Look at this, my mother left me a note. "You can do better. Mom." Not "Love, Mom," not "XO, Mom," just "Mom."

Adult Sheldon: A primary feature of quarks is that they're always bonded together, but in that moment, I felt like a neutrino, destined to be alone forever.
[Montage of young Leonard, Penny, Raj, Howard, Bernadette and Amy at that moment]
Adult Sheldon: Thankfully, I was wrong.

Meemaw: John?
Dr. John Sturgis: Hello.
Meemaw: What- What're you doing?
Dr. John Sturgis: I was doing tai chi and then I realized that I was continually being bombarded by subatomic particles and it behooves me, perhaps, to pay slightly closer attention to them. Maybe "chi" is the ancient Chinese word for the subatomic universe.
Meemaw: You're scaring me, John.
Dr. John Sturgis: Well, there's nothing to be scared of. Tomorrow, somebody will win the Nobel Prize about these particles not me. But I'm experiencing them firsthand [LAUGHS] which could be better.
Meemaw: Why don't you come down and experience them on the floor?
Dr. John Sturgis: I think I just felt a neutrino. [LAUGHING] You know, neutrinos are interesting. They never bond with anything, they're always alone. I think that one went right through my pants.
Meemaw: All right, why don't we go downstairs, and I'll fix us both a nice cup of hot tea and you can tell me all about it. Please?
Dr. John Sturgis: Okay. It was my dream to win the Nobel, and I'm not going to. I bet Sheldon will.
Meemaw: That'll be something.
Dr. John Sturgis: Yeah.

Georgie: A bill? Really?
George: Room and board, buddy.
Georgie: $50 a month for food?
George: The way you eat, I should've gone $50 a week.
Georgie: Laundry services?
George: Your poor mother has to touch your underwear.
Georgie: What's the $10 a month "peema" charge?
George: Oh, P-I-M-A, that's a "Pain in My Ass" tax. My way of getting compensated for you taking years off my life.