Mary: How are we not qualified for anything?
George Sr.: Well, there were a couple.
Mary: I'm not gonna be night security guard at the junkyard, George. You can.
George Sr.: You know I get sleepy.

George Sr.: And Sheldon's fine. You know what he's like. If someone took him, I'm sure they'll bring him right back.

Sheldon: Dad, do you believe that fossils are millions of years old?
George Sr.: I guess. Why?
Sheldon: Well, Mom believes the world was only created 6,000 years ago.
George Sr.: Yeah. So?
Sheldon: Are these differences a sticking point in your marriage?
George Sr.: Not at all.
Sheldon: Why?
George Sr.: Simple. We never talk about it.
Sheldon: So you just avoid discussing topics you don't agree on?
George Sr.: At all costs.

Meemaw: I bowled a new high score last night.
George Sr.: Nice.
Meemaw: I got two turkeys.
Missy: What's a turkey?
Meemaw: It's three strikes in a row.
Missy: Why do they call it a turkey?
Meemaw: Well, when they first invented bowling, they used to just throw frozen turkeys at the pins. Eventually, they switched to balls to cut down on the smell.
George Sr.: Why you lying to her?
Meemaw: I find it keeps my mind sharp.

Adult Sheldon: [hushed] This is why the only bar I frequent is the Genius Bar at the Apple Store.

President Hagemeyer: Okay, so, what's the problem?
Sheldon: I wanted to talk with Dr. Linkletter about puberty.
Dr. Linkletter: And I wanted to avoid litigation.

Missy: Sheldon, there has to be stuff you're excited to do.
Sheldon: Of course. Getting my PhD, winning the Nobel Prize, getting to meet Professor Proton, working with Stephen Hawking.
Missy: Okay, so, when you start to get upset, focus on that stuff.
Sheldon: But... what if I grow up and none of those things ever happen?
Missy: All you can do is try and find out.
Sheldon: Those are the fundamentals of the scientific method.
Missy: No doy.