Missy: I have new information.
Sheldon: What is it?
Missy: I heard them talking about a baby.
Sheldon: Oh, my.
Missy: You know what that means.
Sheldon: Mom's pregnant.
Missy: Exactly.

Sheldon: While Dad's gone, I'm the man of the house, and the man of the house has to enforce the rules.
Missy: The man of the house is about to get his teeth knocked out.
Sheldon: Puberty's made you mean.
Missy: I need to know what happened on my show.
Sheldon: And you'll find out when your privileges are restored.
Missy: I can't wait that long, each episode builds on the last. Imagine a Star Trek that ends with "to be continued," and you don't get to continue.
Sheldon: That would never happen, because I follow the rules.
Missy: You are this close to a purple nurple.
Sheldon: [covers nipples] You leave my nurples alone.

Brenda Sparks: You friends with this girl?
Missy: [scoffs] I wish. She is so popular. One time she said she liked my outfit... I wore it for a week.
Brenda Sparks: [scoffs] What am I gonna do? [both sigh]
Missy: You could tell Billy he's too young to date.
Brenda Sparks: [chuckles softly] That's good. You might be the coolest person in this house.
Missy: Low bar, but thanks.

Sheldon: Why would New Mutants be next to New Teen Titans?
Missy: Because they both start with "New"?
Sheldon: But one's Marvel and the other's DC. Would you put Aquaman and Sub-Mariner next to each other?
Missy: I don't know, they could talk about fish.

George: You ever stop to think maybe she doesn't want to marry a 17-year-old?
Mary: He'll be 18 in March.
George: All right, you're just being ridiculous. [goes back inside]
Mary: I'm being a Christian.
[After Mary walks over and knocks on the garage door, a dozy Georgie opens it]
Mary: When you were born, you were a gift from God but that does not change the fact that I am very mad at you!
Georgie: All right. [closes door]

Mary: When do we get to sit down with her and talk this through?
Georgie: Ah, yeah, here's the thing about that: she ain't real eager to meet y'all.
Mary: Why not?
Meemaw: Did you want to meet George's parents when he knocked you up?
Mary: I was not "knocked up," I was with child. And he's right there. [Georgie waves to Meemaw]

Georgie: Okay, in my defense...
Meemaw: You have no defense. You're an idiot.
Georgie: That was a big part of my defense.