Missy: Where's Mom and Dad?
Sheldon: I don't know. I just got home and no one's here.
Missy: You sure?
Sheldon: It's a tiny house and Dad's a big guy.
Missy: Thanks for the heads-up.
Sheldon: Where are you going?
Missy: To watch R-rated movies until they get back, doy.

George Sr.: What are you doing?
Missy: Watching Sheldon struggle with homework. It's so great.

Missy: So, this Dr. Lee is turning your friends against you?
Sheldon: Essentially.
Missy: Classic move. Most girls you find crying in the school bathroom, that was it.
Sheldon: What do I do?
Missy: Well, you're in a tough spot 'cause your personality is ugh.
Sheldon: There's enough people being mean to me right now.
Missy: Sorry.
Sheldon: Can you help me or not?
Missy: It's you against a bunch of college professors. I don't think you can win this one. [Sheldon starts to walk away] Oh. Do any of them have pimples?
Sheldon: No.
Missy: Too bad, I've done a lot of damage with "pizza face."

Mary: Bless us, Lord, for the food we are about to receive and bless the hands that prepared it.
Missy: And bless Mom.
Mary: Thank you. Amen.
Missy: Amen.
George Jr.: Amen.
Sheldon: She's the hands that prepared it. Your blessing is redundant.
Mary: Let's eat.

George Jr.: Okay, in my defense...
Meemaw: You have no defense. You're an idiot.
George Jr.: That was a big part of my defense.

Mary: Maybe it would be better if you went to your parents with, um, good news first.
Mandy: And what would that be?
Mary: Well... everybody loves a wedding.
George Sr.: Would you stop with that?
Mary: It needs to be discussed.
Mandy: No, it doesn't. I'm having a baby, I don't need to marry another one.
George Jr.: I know I'm young now, but think about it... When you're a dried-up old lady, I'll be your hot trophy husband.
Meemaw: Maybe her dad should put you down.

Billy Sparks: You like meatloaf?
Missy: Yeah, is that what we're having?
Billy Sparks: No, just making dinner conversation.