Meemaw: Do you really think your supercollider could make a black hole?
Dr. John Sturgis: There is about a one-in-a-trillion chance it could.
Meemaw: Friendly advice... next time somebody asks you if your work could destroy the world, just say no.

Georgie: Hey, now that you're treating him like an adult, can I have his allowance?
George: That allowance is for chores, which you already don't do.
Georgie: Come on. We all know I'm your favorite.
Meemaw: You're not even his third favorite.

Mary: Mom, can you make the salad?
Meemaw: Sure.
George: Hey, don't put in any of those little tomatoes.
Meemaw: Hey, I don't tell you how to impersonate a lump of clay. You don't tell me how to make a salad.

Sheldon: Do people know about this?
Meemaw: Sheldon, what's on a person's face is not always what's in their heart.
Sheldon: Well, this changes everything. How do you know who to trust?
Meemaw: You don't. That's what makes life interesting.

Adult Sheldon: [v.o.] We often regret the things we don't say. There's a lot of things I wish I had said to my dad while he was around. That I appreciated him. That I loved him. Which is why I'm grateful for the times I did tell him how I felt.
Sheldon: Tonight was fun.
George: Yeah? Why is that?
Sheldon: Dr. Sturgis was here. Everybody talked about science. It was nice.
George: It was.

President Hagemeyer: Sheldon, Dr. Sturgis quit right before the semester started. He left me in the lurch.
Sheldon: And this is your chance to be the bigger person.
President Hagemeyer: I don't want to be the bigger person. I'll be the small, petty person. That's way more fun.
Sheldon: Please? It would make me really happy if he came back. And you said yourself my happiness is important to the university.
President Hagemeyer: Are you trying to manipulate me?
Sheldon: Hey, being small and petty is fun.

Meemaw: Thanks for inviting John to dinner tonight.
Mary: Oh, my pleasure.
Meemaw: I've been a little bit worried about him. You know, with what happened last time.
Mary: At least he didn't seem unstable when I talked to him.
Meemaw: The man has a doctorate in science, and he's filling people's grocery bags.
Mary: He actually did a really nice job. He put the heavy things on the bottom. He kept the cold things together.
Meemaw: Mary.
Mary: Well, they don't always do that.