Meemaw: What do you two want?
Mr. Lundy: What we want is to make you rich.
Meemaw: Oh, God.

Sheldon: Do people know about this?
Meemaw: Sheldon, what's on a person's face is not always what's in their heart.
Sheldon: Well, this changes everything. How do you know who to trust?
Meemaw: You don't. That's what makes life interesting.

George Jr.: Hey, now that you're treating him like an adult, can I have his allowance?
George Sr.: That allowance is for chores, which you already don't do.
George Jr.: Come on. We all know I'm your favorite.
Meemaw: You're not even his third favorite.

George Sr.: You don't always win in life, he needs to learn that.
Mary: I know, but these are big feelings for a little boy.
George Sr.: They're feelings everybody has. It's part of growing up.
Mary: I guess.
Sheldon: Poodle poop!
Meemaw: Okay. Somebody's got to teach this kid to swear, it's embarrassing.

George Jr.: What is this?
Meemaw: That's the exercise guy Meemaw likes.
George Jr.: I can't believe anyone pays money to watch old people sweat.
Missy: 40 bucks?
George Jr.: They sold over a million of those? At 40 bucks a pop? Do you know how much money that must be?
Missy: I'm not a calculator.
[later:]
George Jr.: 40 times... one million. That's 40 million!
Missy: Whoa.

Adult Sheldon: Behind every great scientist, there were often unsung helpers toiling away in the background. Presenting... "Great Lab Assistants in Scientific History" When Alexander Graham Bell needed an assistant, it was Thomas Augustus Watson who answered the call. [laughs] Get it? "The call". [snickers] Madame Curie's daughter Irène was also her lab assistant. Irène was so dedicated, she died of radiation poisoning. Unlike her sister Ève, who selfishly lived to 102. Lastly, Émile Roux was assistant to Louis Pasteur. When they worked on the rabies vaccine, Roux kept a loaded gun in the lab to shoot Pasteur in the head if he got infected. He never had to, but it's fun to know he would have.
Dr. Linkletter: No, Sheldon. You can't be my lab assistant.
Sheldon: Maybe you weren't paying attention. I'll start over. Behind every great scientist, there was a dedicated as...

Adult Sheldon: While not the lab work I hoped to be doing, it did feel good to be part of an actual experiment. A tedious, menial part that could be performed by a monkey. Or worse, an engineer.