Adult Sheldon: Behind every great scientist, there were often unsung helpers toiling away in the background. Presenting... "Great Lab Assistants in Scientific History" When Alexander Graham Bell needed an assistant, it was Thomas Augustus Watson who answered the call. [laughs] Get it? "The call". [snickers] Madame Curie's daughter Irène was also her lab assistant. Irène was so dedicated, she died of radiation poisoning. Unlike her sister Ève, who selfishly lived to 102. Lastly, Émile Roux was assistant to Louis Pasteur. When they worked on the rabies vaccine, Roux kept a loaded gun in the lab to shoot Pasteur in the head if he got infected. He never had to, but it's fun to know he would have.
Dr. Linkletter: No, Sheldon. You can't be my lab assistant.
Sheldon: Maybe you weren't paying attention. I'll start over. Behind every great scientist, there was a dedicated as...

Adult Sheldon: I didn't realize until years later that my father was only asking questions about lightning and thunder to cheer me up. In fact, he would often pretend to be dumb just to make me feel better.

Adult Sheldon: My father didn't always get the credit he deserved. The advice he gave me actually worked out pretty well. Of course, I never told him.
George: Talked to Billy.
Missy: Why would you do that?
George: No, it was good.
Missy: Stay out of my life.
Adult Sheldon: He may not have been the world's greatest dad. But maybe we weren't the world's greatest kids.

Adult Sheldon: Ignoring things that irritate me isn't my strong suit. Obsessively fixating on them, now that's what gets me out of bed in the morning.

Georgie: What is this?
Meemaw: That's the exercise guy Meemaw likes.
Georgie: I can't believe anyone pays money to watch old people sweat.
Missy: 40 bucks?
Georgie: They sold over a million of those? At 40 bucks a pop? Do you know how much money that must be?
Missy: I'm not a calculator.
[later:]
Georgie: 40 times... one million. That's 40 million!
Missy: Whoa.

Adult Sheldon: While not the lab work I hoped to be doing, it did feel good to be part of an actual experiment. A tedious, menial part that could be performed by a monkey. Or worse, an engineer.

Sheldon: And then he said he wouldn't give me special treatment.
Meemaw: I think what he said is everybody should be treated equally.
Sheldon: I'm sorry, is this Russia? Should we get in line for bread?