Mary: He is gonna freak out about the pain and the needle and the blood.
Dr. Bowers: Yeah, I wouldn't mention that stuff when you tell him.
Mary: Uh, can't you tell him?
Dr. Bowers: [laughs] I'm not gonna tell him.
Mary: But you're his doctor.
Dr. Bowers: And you're his mommy.
Mary: Which means that I have to deal with him all the time. Help me out here.
Dr. Bowers: No.
Mary: Okay. Can we tell him together?
Dr. Bowers: No.
Mary: All right. What if I put your business card, free of charge, in the next church newsletter?

Pastor Jeff: And now George's loving wife Mary would like to say a few words. Mary.
Mary: Thank you, Pastor Jeff. Um... [clears throat] I met George in high school. Well, I was in high school. He was an older man with a motorcycle. [light laughter] I'd like to tell you he caught my eye, but actually it was the motorcycle. [laughter] [voice breaking] I'm sorry, I can't... do this. I am... so angry. [sighs] George and I had our ups and downs, but we were finally in such a good place, and then he... left. [crying] He left all of us. I- How could you do that? [Meemaw stands up] I am so mad at him. I'm mad at God, I'm mad at myself for not trying harder while he was here. [Meemaw goes up to Mary] This wasn't supposed to happen. [Mary sobs] [Meemaw hugs Mary] [Georgie hugs a crying Missy]

Sheldon: Mom, when should I be expecting my testicles?
Woman: [turns around] What is wrong with him?
Mary: Nothing is wrong with him. Now turn around before I knock your lights out.
Sheldon: Hello.

Sheldon: Regardless, I'm not interested in making any more friends.
Mary: Oh, I don't think that's how you really feel.
Sheldon: It is. From now on, it's a hermit's life for me.
Mary: I bet, when you grow up, you will be surrounded by lots of smart, wonderful friends.
Sheldon: I can't see that happening.

Sheldon: So none of you can help me?
Albert Einstein: I believe I can. Sheldon, if I was offered a choice between all the knowledge of the universe or the endless pursuit of it, I would choose the pursuit.
Sheldon: That's very insightful.
Richard Feynman: Hold it, hold it... He didn't come up with that! He stole it from Gotthold Lessing.
Professor Proton: Who's-who's Gotthold Lessing?
Cyndi Lauper: [v.o.] He's an 18th century German philosopher. Now do you mind? We girls are trying to have some fun over here.
Einstein: Apologies.
Richard Feynman: Sorry, Cyndi Lauper.
Stephen Hawking: Our bad.
Professor Proton: I-I like fun.

Georgie: Can I at least change the music we play here?
Dale: What's wrong with the music we play here?
Georgie: Nothing, it's just kind of grandpa music.
Dale: Well, how is this "grandpa music"?
Georgie: Do you listen to it?
Dale: Yeah.
Georgie: Do you have grandchildren?
Dale: Yeah.
Georgie: Do you see where I'm going with this?

Ms. Hutchins: Hi, Sheldon, what can I do for you?
Sheldon: Do you have any books or videos on the Lamaze technique?
Ms. Hutchins: Uh-oh. Georgie get that girl pregnant?
Sheldon: It's for me. I need to have a tooth pulled, and I'd like to do it without putting my brain on drugs.
Ms. Hutchins: Okay.
Sheldon: I've seen that commercial with the egg in the frying pan. Very effective.