Missy: I came this close to having my own room.

Sheldon: While Dad's gone, I'm the man of the house, and the man of the house has to enforce the rules.
Missy: The man of the house is about to get his teeth knocked out.
Sheldon: Puberty's made you mean.
Missy: I need to know what happened on my show.
Sheldon: And you'll find out when your privileges are restored.
Missy: I can't wait that long, each episode builds on the last. Imagine a Star Trek that ends with "to be continued," and you don't get to continue.
Sheldon: That would never happen, because I follow the rules.
Missy: You are this close to a purple nurple.
Sheldon: [covers nipples] You leave my nurples alone.

Sheldon: Uh-oh.
Missy: What?
Sheldon: Listen to this. "French philosopher, mathematician and physicist, Blaise Pascal, argued a rational person should believe God exists because you have everything to gain if you're right, and nothing to lose if you're wrong."
Missy: Sounds right.

Georgie: What kind of homework is it?
Missy: Grammar.
Georgie: I ain't great with grammar.
Missy: Well, grammar's just talking, and we both talk good.

George: And Sheldon's fine. You know what he's like. If someone took him, I'm sure they'll bring him right back.

George: If we take him to a shrink, it feels like we're admitting something's wrong with him.
Mary: He hasn't had solid food in five weeks.
Meemaw: Well, if there is something wrong with him, it ain't constipation.

Missy: Meemaw, are you gonna have any more babies?
Meemaw: Good Lord, no!
Georgie: She's too old to have any more babies.
Meemaw: Don't have to have 'em. You live long enough, your hair and your teeth start falling out, you start wetting the bed, you get to be one.
Georgie: [laughs] That's funny. We're gonna have to put a diaper on you.
Meemaw: You won't be laughing when you're doing it. I might be.