Sheldon: Good luck with your finger painting.
Missy: You're gonna get your ass kicked in high school.
Mary: (flicks Missy on the head) Hey!

Missy: Someone's Underoos are in a knot.
Sheldon: My Underoos are fitting just fine, thank you.
Missy: Then why is there a stick up your butt?
Sheldon: Stop making inquiries about my bottom.
Missy: But I enjoy it.

Missy: Eat dirt. Eat it.
Meemaw: Kick his ass!
Missy: Does it taste good? Huh?
Dale: Yeah, listen to your meemaw. Kick his ass!
Missy: You gonna cry? Huh? Do it. Cry.
Mary: Do something. Break it up.
George Sr.: H-Hang on. She's winning.
Mary: Missy! Missy Cooper, you stop beating up that boy!
Meemaw: Punch him in the nuts!

[Sheldon sits on the top of the couch with his feet on the cushion]
Missy: What are you doing?
Sheldon: I'm practicing the philosophy of cynicism... The ancient Greek view that the rules of society should be ignored.
Missy: If you're gonna break rules, you can do better than that.
Sheldon: How?
[Missy pushes Sheldon off the couch]

Adult Sheldon: That was the first time I held my father's hand. I wouldn't touch my brother's hand until seventeen years later, thanks to the invention of Purell.

Mary: You understand that some people are going to be intimidated by you, because of how smart you are?
Sheldon: Or maybe they'll recognize my intellect and make me their leader.

Sheldon: I smell ammonia. They must've done a thorough cleaning recently. I like that.