Adult Sheldon: The next day, as I walked across campus, I could feel all eyes were on me, judging me for my failure. Look at them laughing at me. It was the closest I ever came to a walk of shame.

Adult Sheldon: I didn't realize until years later that my father was only asking questions about lightning and thunder to cheer me up. In fact, he would often pretend to be dumb just to make me feel better.

Adult Sheldon: My father didn't always get the credit he deserved. The advice he gave me actually worked out pretty well. Of course, I never told him.
George: Talked to Billy.
Missy: Why would you do that?
George: No, it was good.
Missy: Stay out of my life.
Adult Sheldon: He may not have been the world's greatest dad. But maybe we weren't the world's greatest kids.

Adult Sheldon: Ignoring things that irritate me isn't my strong suit. Obsessively fixating on them, now that's what gets me out of bed in the morning.

Sheldon: Hello, Niblingo. Little nibling.
Mandy: What is it, Sheldon?
Sheldon: I was hoping I could try to calm your baby down.
Mandy: Why?
Sheldon: I'm trying new things to build up a tolerance for setbacks and frustration.
Mandy: So you want to use my child for some kind of experiment?
Sheldon: Yes.
Mandy: Okay, here you go.

Dr. John Sturgis: Hang on. Are you familiar with the Fred Astaire song "Pick Yourself Up"?
Sheldon: No.
Dr. John Sturgis: From the beloved musical Swing Time?
Sheldon: Still no.
Dr. John Sturgis: Then prepare to be uplifted. [sings] ♪ Nothing's impossible, I have found ♪ ♪ For when my chin is on the ground ♪ ♪ I pick myself up ♪ ♪ Dust myself off ♪ ♪ Start all over again ♪
Sheldon: I'm not uplifted.
Dr. John Sturgis: [talks] Well, then buckle up for the second verse. [sings] ♪ Don't lose your confidence if you slip ♪ ♪ Be grateful for a pleasant trip ♪ ♪ And pick yourself up ♪ ♪ Dust yourself off ♪ ♪ Start all over again. ♪

Mary: It's okay, sweetie, Nana's here.
Georgie: Nana? Who picked that?
Mary: I did.
Georgie: Why ain't you another meemaw?
Meemaw: 'Cause I'm the only meemaw.