Sheldon: It'll be great to have him back at the university.
Meemaw: Actually... doesn't sound like he's going back.
Sheldon: Why not?
Meemaw: He's a little upset about getting fired, and... says he's ready for a change.
Sheldon: An old person trying something new? That's funny.
Meemaw: You'll be old one day, too, pal.
Sheldon: I already don't like new things. Bring it on.

Sheldon: I started working on this presentation to address specific ethical dilemmas. The laws of robotics, whether torture can be justified, and cloning people for fun and spare parts. But I realized before resolving any of these moral quandaries, the real decision is who gets to decide. Do we put it up for a vote? Does everyone get to decide for themselves? Should it be by committee? Is that committee elected or appointed? You see where I'm going? You probably don't. For the smartest decision, we need the smartest person. Ladies and gentlemen, in the field of scientific ethics, we can't rely on democracy or plutocracy. We need an autocracy, or to be more precise, a "Sheldocracy." [slams fist] [military march plays]
Dr. John Sturgis: Um, I don't think this was the assignment.
Sheldon: Sorry, Dr. Sturgis, I pick the assignments now. Everybody, for next class, I want 500 words on what you can do to further the Sheldocracy. Punishment for typos will be severe.
Dr. John Sturgis: Class dismissed.
Sheldon: Hey, that's my line.
Dr. John Sturgis: No, it isn't.
Sheldon: Why don't you see me after class. Class dismissed.

Principal Petersen: Our next young speaker needs no introduction, but that didn't stop him from writing one and making me read it. [laughter] "Fun fact." [audience groans, murmurs] I hear you. "The word 'valedictorian' is from the Latin 'valedicere,' meaning 'to say farewell.' It is primarily used in the United States, Canada, the Philippines and Armenia." Maybe that fact's more fun in Armenia. Please welcome your valedictorian, Sheldon Cooper.
Mary: Yay, Shelly!
Sheldon: Hello. I'm not very comfortable speaking in front of crowds. But there's a technique to reduce stage fright by focusing on one person in the audience and delivering your speech just to them. That's what I'll be doing today. If it weren't for this person, I wouldn't be here right now. They've taught me a lot, and it's by their example that I found the courage to move forward into this new and exciting chapter of my life. Missy... ...this is for you. Change can be scary, but I know we're going to be fine... ...because like you said, "It's okay to be scared. We just have to do it anyway." So if any of my fellow graduates are nervous about the future, know that you're not alone. I suggest you all try to be as brave as my twin sister. That's my plan. Missy, I wish I could give you advice about middle school, but I was so smart, I skipped it. If you make it to high school, we'll talk. Thank you. [applause]

Mary: You understand that some people are going to be intimidated by you, because of how smart you are?
Sheldon: Or maybe they'll recognize my intellect and make me their leader.

Adult Sheldon: [v.o.] We often regret the things we don't say. There's a lot of things I wish I had said to my dad while he was around. That I appreciated him. That I loved him. Which is why I'm grateful for the times I did tell him how I felt.
Sheldon: Tonight was fun.
George: Yeah? Why is that?
Sheldon: Dr. Sturgis was here. Everybody talked about science. It was nice.
George: It was.

President Hagemeyer: Sheldon, Dr. Sturgis quit right before the semester started. He left me in the lurch.
Sheldon: And this is your chance to be the bigger person.
President Hagemeyer: I don't want to be the bigger person. I'll be the small, petty person. That's way more fun.
Sheldon: Please? It would make me really happy if he came back. And you said yourself my happiness is important to the university.
President Hagemeyer: Are you trying to manipulate me?
Sheldon: Hey, being small and petty is fun.

Meemaw: The man has a doctorate in science, and he's filling people's grocery bags.
Mary: He actually did a really nice job. He put the heavy things on the bottom. He kept the cold things together.
Meemaw: Mary.
Mary: Well, they don't always do that.