Sheldon: It's funny. This morning, I couldn't get out of bed, and now I stand before a whole new exciting field of study.
Meemaw: Well, maybe instead of making this big switch, you could study both. You could be physics-philosophy guy.
Sheldon: You sound like a logical positivist. That's a branch of philosophy that maintains the best way to philosophize is through science.
Meemaw: Well, there you go. Do that.
Sheldon: It may be too early to specialize. I've only been a philosopher for 15 minutes.
Meemaw: Did you notice Dr. Linkletter didn't look too thrilled about you leaving science?
Sheldon: He never looks thrilled about anything. I think that's just his face. [Meemaw turns to look at Sheldon] That's the face.

Principal Petersen: Our next young speaker needs no introduction, but that didn't stop him from writing one and making me read it. [laughter] "Fun fact." [audience groans, murmurs] I hear you. "The word 'valedictorian' is from the Latin 'valedicere,' meaning 'to say farewell.' It is primarily used in the United States, Canada, the Philippines and Armenia." Maybe that fact's more fun in Armenia. Please welcome your valedictorian, Sheldon Cooper.
Mary: Yay, Shelly!
Sheldon: Hello. I'm not very comfortable speaking in front of crowds. But there's a technique to reduce stage fright by focusing on one person in the audience and delivering your speech just to them. That's what I'll be doing today. If it weren't for this person, I wouldn't be here right now. They've taught me a lot, and it's by their example that I found the courage to move forward into this new and exciting chapter of my life. Missy... ...this is for you. Change can be scary, but I know we're going to be fine... ...because like you said, "It's okay to be scared. We just have to do it anyway." So if any of my fellow graduates are nervous about the future, know that you're not alone. I suggest you all try to be as brave as my twin sister. That's my plan. Missy, I wish I could give you advice about middle school, but I was so smart, I skipped it. If you make it to high school, we'll talk. Thank you. [applause]

Missy: What's it like to not believe in God?
Sheldon: It's great. Big fan.
Missy: Are you ever afraid you're wrong?
Sheldon: About religion? Never. About other things? Also never.

Ms. MacElroy: Now, can anyone tell me why Melville shifts the narrative voice from Ishmael to Ahab? [Ms. MacElroy waits for somebody else to raise their hand] Sheldon.
Sheldon: I have a tummyache. I'd like to see the nurse.
Derek: A "tummyache"?
Sheldon: Yes, Derek, I have a tummy and it aches. Ergo, tummyache.
Derek: Ergo?
Sheldon: It's Latin, Derek.
Ms. MacElroy: Go to the nurse.
Sheldon: And to answer your question, the shifting point of view grants the reader a broader perspective of events than typically allowed by first-person narration.
Ms. MacElroy: Where were we?
Sheldon: And "ergo" is Latin for "hence," Derek.

Meemaw: Okay, I'm here. What's up?
George Sr.: Sheldon won't get out of bed, and I'm gonna be late for work. He's gonna be late for school.
Meemaw: So you want me to get him up and drive him?
George Sr.: Yeah.
Meemaw: I like it better when I just come eat your food and leave.

Meemaw: Shelly, Dr. Sturgis is on the line for you.
Sheldon: Maybe he is, maybe he isn't, but very well. [takes phone] Hello?
Dr. John Sturgis: [on the phone] Hi, Sheldon. I hear you're going through some sort of existential crisis.
Sheldon: I suppose so. I just don't know if we can tell what's real or not. And if nothing's real, I don't know what to think or if I'm even thinking at all.
Dr. John Sturgis: I went through something similar once.
Sheldon: Really? What happened?
Dr. John Sturgis: I was trekking through the Amazon, and I saw two frogs, one hallucinogenic and the other not. [chuckles] I tried to lick the normal one, and, by mistake, I licked the hallucinogenic one. It really rocked my world.
Sheldon: Why would you lick either of them?
Dr. John Sturgis: I'm not sure. Probably low blood sugar. But the point is, I also lost track of reality.
Sheldon: How did you handle it?
Dr. John Sturgis: I saw a jaguar, and I realized I didn't care if it was real or not. I just hauled my tushy out of there.
Sheldon: I appreciate the call. I'm giving you back to my meemaw now.
Dr. John Sturgis: Bye!
Meemaw: [quietly on the phone] Hey, John, any luck?
Dr. John Sturgis: Not unless you have access to a jaguar.
Meemaw: I don't think I do.
Dr. John Sturgis: Really, any jungle cat will do.

Adult Sheldon: While my meemaw wasn't able to acquire a jungle cat, the idea of tormenting a child did tickle her Texan fancy.
Meemaw: [singsong] Sheldon. [chicken clucking] I have someone else who wants to talk to you.
Sheldon: What are you doing with that filthy thing?
Meemaw: Why do you care? If nothing is real, then neither is the chicken. [Sheldon jumps out of bed] Oh. Good. We're standing now. That's progress.
Sheldon: Get her out of here.
Meemaw: Well, I would, but... [chuckles] apparently, I can't know what "here" is. So maybe I could just... set her on your bed.
Sheldon: Okay! Okay. I'll get dressed.
Meemaw: Make it snappy.
Sheldon: This still doesn't solve my existential crisis.
Meemaw: Say what? You want to hold her?
Sheldon: [gasps] No.
Meemaw: Less talk. More pants.